TY - JOUR
T1 - The Effect of Pomegranate Juice and Sumac Consumption in the Treatment of Outpatients with COVID-19
AU - Forouzanfar, Fatemeh
AU - Ahmadpoor, Mohammadreza
AU - Farahi, Mostafa Moshirian
AU - Hadianfar, Ali
AU - Sahebkar, Amirhossein
AU - Esmaily, Habibollah
AU - Nematy, Mohsen
AU - Rakhshandeh, Hassan
N1 - Publisher Copyright:
© 2022 Fatemeh Forouzanfar et al.
PY - 2022
Y1 - 2022
N2 - Introduction. COVID-19, an epidemic of coronavirus infection, has become a major global threat. The coronavirus mainly targets the human respiratory system, followed by cytokine storm, and altered immune responses associated with disease progression and adverse outcomes. Sumac and pomegranate juice are rich in bioactive compounds, which potentially have antiviral activities. This study is aimed at investigating the effect of a diet based on the use of sumac and pomegranate juice on the treatment of outpatients with COVID-19. Methods. In this study, 182 outpatients with COVID-19 were randomly divided into two groups receiving a diet containing pomegranate juice and sumac along with standard treatment and the control group (group 2) receiving standard treatment. Results. Consumption of a diet containing pomegranate juice and sumac in outpatients with COVID-19, who were receiving standard-of-care treatment, led to a significant decrease in fever, chills, cough, weakness, smell and taste disorders, shortness of breath, diarrhea, nausea and vomiting, and abdominal pain compared with outpatients with COVID-19 who received only standard treatment. Conclusion. Clinical trials of outpatients have limitations such as patients' resilience to post-COVID-19 follow-up. However, the use of pomegranate juice and sumac can be efficacious in reducing COVID-19 symptoms. This trial is registered with IRCT20190406043175N3.
AB - Introduction. COVID-19, an epidemic of coronavirus infection, has become a major global threat. The coronavirus mainly targets the human respiratory system, followed by cytokine storm, and altered immune responses associated with disease progression and adverse outcomes. Sumac and pomegranate juice are rich in bioactive compounds, which potentially have antiviral activities. This study is aimed at investigating the effect of a diet based on the use of sumac and pomegranate juice on the treatment of outpatients with COVID-19. Methods. In this study, 182 outpatients with COVID-19 were randomly divided into two groups receiving a diet containing pomegranate juice and sumac along with standard treatment and the control group (group 2) receiving standard treatment. Results. Consumption of a diet containing pomegranate juice and sumac in outpatients with COVID-19, who were receiving standard-of-care treatment, led to a significant decrease in fever, chills, cough, weakness, smell and taste disorders, shortness of breath, diarrhea, nausea and vomiting, and abdominal pain compared with outpatients with COVID-19 who received only standard treatment. Conclusion. Clinical trials of outpatients have limitations such as patients' resilience to post-COVID-19 follow-up. However, the use of pomegranate juice and sumac can be efficacious in reducing COVID-19 symptoms. This trial is registered with IRCT20190406043175N3.
UR - http://www.scopus.com/inward/record.url?scp=85143749921&partnerID=8YFLogxK
U2 - 10.1155/2022/6850342
DO - 10.1155/2022/6850342
M3 - Article
C2 - 36505757
AN - SCOPUS:85143749921
SN - 0962-9351
VL - 2022
JO - Mediators of Inflammation
JF - Mediators of Inflammation
M1 - 6850342
ER -
