The effect of non-invasive ventilation on intra-abdominal pressure

Adrian Regli, Reoch Nanda, Jan P. Braun, Massimo Girardis, Martin Max, Manu L. Malbrain, Bart L. De Keulenaer

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Background: Non-invasive ventilation is a well-established treatment modality in patients with respiratory failure of different aetiologies. A previous case report described how non-invasive ventilation caused gastric distension and intra-abdominal hypertension with subsequent cardio-respiratory arrest and clinical recovery following resuscitative efforts including gastric decompression with a nasogastric tube. Methods: The aim of this prospective multicentre observational study was to assess the effect of non-invasive ventilation on intra-abdominal pressure. Following informed consent, intra-abdominal pressure and PaCO2were measured before and after the application of non-invasive ventilation for up to three days in critically ill patients requiring non-invasive ventilation. Results: Thirty-five patients were enrolled; mean (±SD) age of 67.8 (±12.5) years, median (interquartile range) body mass index of 27.9 (24.5-30.0) kg m-2, Acute Physiology and Chronic Health Evaluation II score of 15.8 (±6.4). On admission and after 24 hours of non-invasive ventilation, intra-abdominal pressure was 11.0 (7.5-15.0) mm Hg and 11.0 (8.5-14.5) mm Hg (P = 0.82) and PaCO2was 44.4 (±11.4) mm Hg and 51.3 (±14.3) mm Hg (P = 0.19), respectively. Conclusions: The application of non-invasive ventilation was not associated with an increase in intra-abdominal pressure over 72 hours in this small observational study. Thus, it appears that intra-abdominal pressure does not frequently increase when applying non-invasive ventilation in critically ill patients with respiratory failure.

Original languageEnglish
Pages (from-to)30-33
Number of pages4
JournalAnaesthesiology Intensive Therapy
Issue number1
Publication statusPublished - 2022


Dive into the research topics of 'The effect of non-invasive ventilation on intra-abdominal pressure'. Together they form a unique fingerprint.

Cite this