The effect of implanting an antigen release device on lactoferrin concentration in serum and milk

J.B. Cheng, J.Q. Wang, D.P. Bu, G.L. Liu, S.P.A. Iaschi, C.G. Zhang, H.Y. Wei, L.Y. Zhou, J.Z. Wang, Guan Tay

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The objective of this study was to evaluate the effect of implanting an Antigen Release Devices (ARD) into dairy cows during the lactation cycle to induce an immune response. Subsequently, the concentrations of lactoferrin in serum and milk were measured. Forty healthy adult Chinese Holstein cows were divided into two equal groups: a test group and a control group. Animals in the test group received ARD implants, whereas the control roup animals were not treated. An even spread across the two groups was maintained with animal selection based oil parity, the lactation days and milk yields. The concentrations of lactoferrin in the serum and milk of all forty animals were measured using an Enzyme-Linked Immunosorbent Assay (ELISA). The results show that the implantation of an ARD did not significantly increase the concentration of lactoferrin in the serum and milk throughout the whole experiment period except on two occasions. The levels of lactoferrin in the milk and serum significantly increased oil day 7 and on day 11 after implantation (p
Original languageEnglish
Pages (from-to)819-824
JournalJournal of Veterinary Medical Science
Issue number8
Publication statusPublished - 2008


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