Abstract
Cytomegalovirus (CMV) has a worldwide prevalence of 80-100%, and is a common opportunistic infection encountered by renal transplant recipients. CMV becomes latent and may be reactivated without acute symptoms at any lime post-transplant , but its effects on health outcomes are unclear. This thesis demonstrates that CMV has the unique ability to Imprint upon natural killer cell and T cell receptor expression in transplant recipients, with smaller effects in healthy controls. These changes to immune cells could play a role In the development of cardiovascular disease.
| Original language | English |
|---|---|
| Qualification | Doctor of Philosophy |
| Awarding Institution |
|
| Supervisors/Advisors |
|
| Award date | 9 Dec 2016 |
| Publication status | Unpublished - 2016 |
Access to Document
- THESIS - DOCTOR OF PHILOSOPHY - MAKWANA Nandini Bharatkumar - 2016
This work is protected by Copyright. You may print or download ONE copy of this document for the purpose of your own non-commercial research or study. Any other use requires permission from the copyright owner. The Copyright Act requires you to attribute any copyright works you quote or paraphrase.