The disability rate of 5-year post-stroke and its correlation factors: A national survey in China

Yang Yang, Yu Zhi Shi, Ning Zhang, Shuo Wang, Gabor S. Ungvari, Chee H. Ng, Yi Long Wang, Xing Quan Zhao, Yong Jun Wang, Chun Xue Wang, Yu-Tao Xiang

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    29 Citations (Scopus)


    Few studies on long-term functional outcome have been conducted in post-stroke patients in China. The objective of this study was to conduct a nationwide survey in China to investigate the 5-year prevalence of post-stroke disability and its correlation factors. A total of 893 patients with ischemic stroke were included. Demographic, clinical and neuro-imaging information were collected with standardized instruments that assessed stroke severity, depression, cognitive impairment, stroke recurrence and physical disability. Disability was assessed with the modified Ranking Score (mRS), of which a cutoff score ≤2 indicates disability. Statistical analysis included chi-square tests, two independent samples t-tests, Mann-Whitney U test and multiple logistic regression analysis. The frequency of disability in this study population was 45%. Multivariate analyses revealed that older age, lower education level, previous history of stroke, stroke severity at admission, depression, cognitive impairment at 3 months, and stroke recurrence within 5 years follow up were all significantly associated with post-stroke disability. The disability rate in 5-year post-stroke was high in Chinese patients. Treatment of depression, secondary prevention of stroke and rehabilitation may benefit disabled patients with stroke in China.

    Original languageEnglish
    Article numbere0165341
    JournalPLoS One
    Issue number11
    Publication statusPublished - 1 Nov 2016

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