The development and distribution of alpha-bungarotoxin binding sites in rat tectal transplants.

M. M. Tan, A. R. Harvey

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The development and distribution of alpha-bungarotoxin (alpha-BTX) binding sites in tectal grafts was examined autoradiographically using the radioligand [125I]-alpha-BTX. High alpha-BTX binding was observed in localized areas within grafts; these areas corresponded to regions which contained high acetylcholinesterase activity and received retinal input. Receptor differentiation also occurred in the absence of specific host afferents. The graft data show that, as in normal superior colliculus, development of high alpha-BTX binding is limited to areas containing presumptive superficial layer cells.

Original languageEnglish
Pages (from-to)293-298
Number of pages6
JournalBrain Research
Volume433
Issue number2
Publication statusPublished - 1 Dec 1987

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