The design of next-generation cardiovascular devices: an investigation into a bio-inspired, controllable, origami stent-graft

Endovascular aortic repair, which initially targeted abdominal aortic aneurysms, has evolved to encompass the entire aorta, driven by advancements in stent graft (SG) technology. However, the commercial SGs' conventional manufacturing methods, simplistic designs, and materials have raised concerns about device-related complications. It is imperative to embrace advanced techniques like 4D printing, smart materials, and innovative designs to shape the future of cardiovascular implant production. This thesis attempts to advance the knowledge in the development of next generation SG using through incorporating the parametric modelling for bioinspired origami design, a nanocomposite material system, 4D printing techniques and a magnetic control system.