TY - JOUR
T1 - The Burden of Cardiovascular Diseases Among US States, 1990-2016
AU - Global Burden of Cardiovascular Diseases Collaboration
AU - Roth, Gregory A.
AU - Johnson, Catherine O.
AU - Abate, Kalkidan Hassen
AU - Abd-Allah, Foad
AU - Ahmed, Muktar
AU - Alam, Khurshid
AU - Alam, Tahiya
AU - Alvis-Guzman, Nelson
AU - Ansari, Hossein
AU - Ärnlöv, Johan
AU - Atey, Tesfay Mehari
AU - Awasthi, Ashish
AU - Awoke, Tadesse
AU - Barac, Aleksandra
AU - Bärnighausen, Till
AU - Bedi, Neeraj
AU - Bennett, Derrick
AU - Bensenor, Isabela
AU - Biadgilign, Sibhatu
AU - Castañeda-Orjuela, Carlos
AU - Catalá-López, Ferrán
AU - Davletov, Kairat
AU - Dharmaratne, Samath
AU - Ding, Eric L.
AU - Dubey, Manisha
AU - Faraon, Emerito Jose Aquino
AU - Farid, Talha
AU - Farvid, Maryam S.
AU - Feigin, Valery
AU - Fernandes, João
AU - Frostad, Joseph
AU - Gebru, Alemseged
AU - Geleijnse, Johanna M.
AU - Gona, Philimon Nyakauru
AU - Griswold, Max
AU - Hailu, Gessessew Bugssa
AU - Hankey, Graeme J.
AU - Hassen, Hamid Yimam
AU - Havmoeller, Rasmus
AU - Hay, Simon
AU - Heckbert, Susan R.
AU - Irvine, Caleb Mackay Salpeter
AU - James, Spencer Lewis
AU - Jara, Dube
AU - Kasaeian, Amir
AU - Khan, Abdur Rahman
AU - Khera, Sahil
AU - Khoja, Abdullah T.
AU - Khubchandani, Jagdish
AU - Kim, Daniel
AU - Kolte, Dhaval
AU - Lal, Dharmesh
AU - Larsson, Anders
AU - Linn, Shai
AU - Lotufo, Paulo A.
AU - El Razek, Hassan Magdy Abd
AU - Mazidi, Mohsen
AU - Meier, Toni
AU - Mendoza, Walter
AU - Mensah, George A.
AU - Meretoja, Atte
AU - Mezgebe, Haftay Berhane
AU - Mirrakhimov, Erkin
AU - Mohammed, Shafiu
AU - Moran, Andrew Edward
AU - Nguyen, Grant
AU - Nguyen, Minh
AU - Ong, Kanyin Liane
AU - Owolabi, Mayowa
AU - Pletcher, Martin
AU - Pourmalek, Farshad
AU - Purcell, Caroline A.
AU - Qorbani, Mostafa
AU - Rahman, Mahfuzar
AU - Rai, Rajesh Kumar
AU - Ram, Usha
AU - Reitsma, Marissa Bettay
AU - Renzaho, Andre M.N.
AU - Rios-Blancas, Maria Jesus
AU - Safiri, Saeid
AU - Salomon, Joshua A.
AU - Sartorius, Benn
AU - Sepanlou, Sadaf Ghajarieh
AU - Shaikh, Masood Ali
AU - Silva, Diego
AU - Stranges, Saverio
AU - Tabarés-Seisdedos, Rafael
AU - Atnafu, Niguse Tadele
AU - Thakur, J. S.
AU - Topor-Madry, Roman
AU - Truelsen, Thomas
AU - Tuzcu, E. Murat
AU - Tyrovolas, Stefanos
AU - Ukwaja, Kingsley Nnanna
AU - Vasankari, Tommi
AU - Vlassov, Vasiliy
AU - Vollset, Stein Emil
AU - Wakayo, Tolassa
AU - Weintraub, Robert
AU - Wolfe, Charles
AU - Workicho, Abdulhalik
AU - Xu, Gelin
AU - Yadgir, Simon
AU - Yano, Yuichiro
AU - Yip, Paul
AU - Yonemoto, Naohiro
AU - Younis, Mustafa
AU - Yu, Chuanhua
AU - Zaidi, Zoubida
AU - El Sayed Zaki, Maysaa
AU - Zipkin, Ben
AU - Afshin, Ashkan
AU - Gakidou, Emmanuela
AU - Lim, Stephen S.
AU - Mokdad, Ali H.
AU - Naghavi, Mohsen
AU - Vos, Theo
AU - Murray, Christopher J.L.
PY - 2018/5/1
Y1 - 2018/5/1
N2 - Importance: Cardiovascular disease (CVD) is the leading cause of death in the United States, but regional variation within the United States is large. Comparable and consistent state-level measures of total CVD burden and risk factors have not been produced previously.Objective: To quantify and describe levels and trends of lost health due to CVD within the United States from 1990 to 2016 as well as risk factors driving these changes.Design, Setting, and Participants: Using the Global Burden of Disease methodology, cardiovascular disease mortality, nonfatal health outcomes, and associated risk factors were analyzed by age group, sex, and year from 1990 to 2016 for all residents in the United States using standardized approaches for data processing and statistical modeling. Burden of disease was estimated for 10 groupings of CVD, and comparative risk analysis was performed. Data were analyzed from August 2016 to July 2017.Exposures: Residing in the United States.Main Outcomes and Measures: Cardiovascular disease disability-adjusted life-years (DALYs).Results: Between 1990 and 2016, age-standardized CVD DALYs for all states decreased. Several states had large rises in their relative rank ordering for total CVD DALYs among states, including Arkansas, Oklahoma, Alabama, Kentucky, Missouri, Indiana, Kansas, Alaska, and Iowa. The rate of decline varied widely across states, and CVD burden increased for a small number of states in the most recent years. Cardiovascular disease DALYs remained twice as large among men compared with women. Ischemic heart disease was the leading cause of CVD DALYs in all states, but the second most common varied by state. Trends were driven by 12 groups of risk factors, with the largest attributable CVD burden due to dietary risk exposures followed by high systolic blood pressure, high body mass index, high total cholesterol level, high fasting plasma glucose level, tobacco smoking, and low levels of physical activity. Increases in risk-deleted CVD DALY rates between 2006 and 2016 in 16 states suggest additional unmeasured risks beyond these traditional factors.Conclusions and Relevance: Large disparities in total burden of CVD persist between US states despite marked improvements in CVD burden. Differences in CVD burden are largely attributable to modifiable risk exposures.
AB - Importance: Cardiovascular disease (CVD) is the leading cause of death in the United States, but regional variation within the United States is large. Comparable and consistent state-level measures of total CVD burden and risk factors have not been produced previously.Objective: To quantify and describe levels and trends of lost health due to CVD within the United States from 1990 to 2016 as well as risk factors driving these changes.Design, Setting, and Participants: Using the Global Burden of Disease methodology, cardiovascular disease mortality, nonfatal health outcomes, and associated risk factors were analyzed by age group, sex, and year from 1990 to 2016 for all residents in the United States using standardized approaches for data processing and statistical modeling. Burden of disease was estimated for 10 groupings of CVD, and comparative risk analysis was performed. Data were analyzed from August 2016 to July 2017.Exposures: Residing in the United States.Main Outcomes and Measures: Cardiovascular disease disability-adjusted life-years (DALYs).Results: Between 1990 and 2016, age-standardized CVD DALYs for all states decreased. Several states had large rises in their relative rank ordering for total CVD DALYs among states, including Arkansas, Oklahoma, Alabama, Kentucky, Missouri, Indiana, Kansas, Alaska, and Iowa. The rate of decline varied widely across states, and CVD burden increased for a small number of states in the most recent years. Cardiovascular disease DALYs remained twice as large among men compared with women. Ischemic heart disease was the leading cause of CVD DALYs in all states, but the second most common varied by state. Trends were driven by 12 groups of risk factors, with the largest attributable CVD burden due to dietary risk exposures followed by high systolic blood pressure, high body mass index, high total cholesterol level, high fasting plasma glucose level, tobacco smoking, and low levels of physical activity. Increases in risk-deleted CVD DALY rates between 2006 and 2016 in 16 states suggest additional unmeasured risks beyond these traditional factors.Conclusions and Relevance: Large disparities in total burden of CVD persist between US states despite marked improvements in CVD burden. Differences in CVD burden are largely attributable to modifiable risk exposures.
UR - http://www.scopus.com/inward/record.url?scp=85049079307&partnerID=8YFLogxK
U2 - 10.1001/jamacardio.2018.0385
DO - 10.1001/jamacardio.2018.0385
M3 - Article
C2 - 29641820
VL - 3
SP - 375
EP - 389
JO - JAMA Cardiology
JF - JAMA Cardiology
SN - 2380-6583
IS - 5
ER -