The biological function, targeting specificity and redesign of PPR RNA editing factors

Yueming Sun

doi:10.4225/23/5acad400bd380

The biological function, targeting specificity and redesign of PPR RNA editing factors

Yueming Sun

School of Molecular Sciences

Research output: Thesis › Doctoral Thesis

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Abstract

This work identifies new pentatricopeptide repeat (PPR) RNA editing factors in chloroplasts, investigates their off-target effects, and characterises functions of modified PPR editing factors in plants. This work gains insights into the targeting specificity of PPR editing factors and the functional diversity of PPR motifs. This work demonstrates the challenges to be overcome in
retargeting PPR editing factors.

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	The University of Western Australia
Supervisors/Advisors	Small, Ian, Supervisor Bond, Charlie, Supervisor Colas des Francs-Small, Catherine, Supervisor Bernath-Levin, Kalia, Supervisor Waters, Mark, Supervisor
Thesis sponsors	Australian Government Research Training Program
Award date	7 Dec 2017
DOIs	https://doi.org/10.4225/23/5acad400bd380
Publication status	Unpublished - 2017

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Cite this

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title = "The biological function, targeting specificity and redesign of PPR RNA editing factors",

abstract = "This work identifies new pentatricopeptide repeat (PPR) RNA editing factors in chloroplasts, investigates their off-target effects, and characterises functions of modified PPR editing factors in plants. This work gains insights into the targeting specificity of PPR editing factors and the functional diversity of PPR motifs. This work demonstrates the challenges to be overcome in retargeting PPR editing factors. ",

keywords = "PPR, RNA editing, Arabidopsis, Chloroplast",

author = "Yueming Sun",

year = "2017",

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AU - Sun, Yueming

PY - 2017

Y1 - 2017

N2 - This work identifies new pentatricopeptide repeat (PPR) RNA editing factors in chloroplasts, investigates their off-target effects, and characterises functions of modified PPR editing factors in plants. This work gains insights into the targeting specificity of PPR editing factors and the functional diversity of PPR motifs. This work demonstrates the challenges to be overcome in retargeting PPR editing factors.

AB - This work identifies new pentatricopeptide repeat (PPR) RNA editing factors in chloroplasts, investigates their off-target effects, and characterises functions of modified PPR editing factors in plants. This work gains insights into the targeting specificity of PPR editing factors and the functional diversity of PPR motifs. This work demonstrates the challenges to be overcome in retargeting PPR editing factors.

KW - PPR

KW - RNA editing

KW - Arabidopsis

KW - Chloroplast

U2 - 10.4225/23/5acad400bd380

DO - 10.4225/23/5acad400bd380

M3 - Doctoral Thesis

ER -

The biological function, targeting specificity and redesign of PPR RNA editing factors

Abstract

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