The Avidity Game: Selecting Natural-Born Killers

Christopher E. Andoniou; Iona S. Schuster; Mariapia A. Degli-Esposti

doi:10.1016/j.immuni.2019.05.018

The Avidity Game: Selecting Natural-Born Killers

Christopher E. Andoniou, Iona S. Schuster, Mariapia A. Degli-Esposti

Centre for Ophthalmology and Visual Science (affiliated with the Lions Eye Institute)

Research output: Contribution to journal › Editorial › peer-review

Abstract

Natural killer (NK) cells display some features equivalent to those of adaptive immune effectors, but the molecular processes underlying these adaptive-like characteristics are just beginning to be defined. In this issue of Immunity, Adams et al. (2019) and Grassmann et al. (2019) report that avidity selection for Ly49H governs the expansion, differentiation, and function of NK cells after cytomegalovirus infection.

Original language	English
Pages (from-to)	1337-1339
Number of pages	3
Journal	Immunity
Volume	50
Issue number	6
DOIs	https://doi.org/10.1016/j.immuni.2019.05.018
Publication status	Published - 18 Jun 2019

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title = "The Avidity Game: Selecting Natural-Born Killers",

abstract = "Natural killer (NK) cells display some features equivalent to those of adaptive immune effectors, but the molecular processes underlying these adaptive-like characteristics are just beginning to be defined. In this issue of Immunity, Adams et al. (2019) and Grassmann et al. (2019) report that avidity selection for Ly49H governs the expansion, differentiation, and function of NK cells after cytomegalovirus infection.",

author = "Andoniou, {Christopher E.} and Schuster, {Iona S.} and Degli-Esposti, {Mariapia A.}",

year = "2019",

month = jun,

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doi = "10.1016/j.immuni.2019.05.018",

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journal = "Immunity",

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T2 - Selecting Natural-Born Killers

AU - Andoniou, Christopher E.

AU - Schuster, Iona S.

AU - Degli-Esposti, Mariapia A.

PY - 2019/6/18

Y1 - 2019/6/18

N2 - Natural killer (NK) cells display some features equivalent to those of adaptive immune effectors, but the molecular processes underlying these adaptive-like characteristics are just beginning to be defined. In this issue of Immunity, Adams et al. (2019) and Grassmann et al. (2019) report that avidity selection for Ly49H governs the expansion, differentiation, and function of NK cells after cytomegalovirus infection.

AB - Natural killer (NK) cells display some features equivalent to those of adaptive immune effectors, but the molecular processes underlying these adaptive-like characteristics are just beginning to be defined. In this issue of Immunity, Adams et al. (2019) and Grassmann et al. (2019) report that avidity selection for Ly49H governs the expansion, differentiation, and function of NK cells after cytomegalovirus infection.

U2 - 10.1016/j.immuni.2019.05.018

DO - 10.1016/j.immuni.2019.05.018

M3 - Editorial

C2 - 31216454

SN - 1074-7613

VL - 50

SP - 1337

EP - 1339

JO - Immunity

JF - Immunity

IS - 6

ER -

The Avidity Game: Selecting Natural-Born Killers

Abstract

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