The association between post-stroke depression, aphasia, and physical independence in stroke patients at 3-month follow-up

Shuo Wang, Chun Xue Wang, Ning Zhang, Yu Tao Xiang, Yang Yang, Yu Zhi Shi, Yi Ming Deng, Mei Fang Zhu, Fei Liu, Ping Yu, Gabor S. Ungvari, Chee H. Ng

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3 Citations (Scopus)

Abstract

Objective: Few studies have examined the association between post-stroke depression (PSD), aphasia, and physical independence in Chinese patients. This study investigated the above association in stroke patients in China at 3-month follow-up. Methods: Altogether 270 patients within 14 days after ischemic stroke were recruited and followed up at 3 months. PSD, aphasia, and physical functional status were measured using the Stroke Aphasia Depression Questionnaire (SADQ), Western Aphasia Battery (WAB), and modified Rankin Scale (mRS), respectively. Patients with mRS total score > 2 were considered as having "physical dependence." Results: Out of 248 patients at 3-month follow up, 119 (48%) were rated as having physical dependence. Multiple logistic regression analyses revealed that female (p = 0.04; OR = 2.2; 95% CI: 1.0-5.1), more severe stroke at admission (p < 0.01; OR = 1.4; 95% CI: 1.3-1.5), and more severe PSD at 3 months (p = 0.01; OR = 1.05; 95% CI: 1.01-1.1) were independently associated with physical dependence at 3 months. Conclusions: Greater PSD and stroke severity were independently associated with physical dependence at 3 months after stroke. Aphasia was also associated with physical dependence but the relationship was not significant. Early and effective depression screening, treatment and stroke rehabilitation appear to be important to improve the physical outcome and reduce the burden of stroke survivors.

Original languageEnglish
Article number374
JournalFrontiers in Psychiatry
Volume9
Issue numberAUG
DOIs
Publication statusPublished - 20 Aug 2018
Externally publishedYes

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Aphasia
Stroke
Survivors
China
Logistic Models
Regression Analysis

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Wang, Shuo ; Wang, Chun Xue ; Zhang, Ning ; Xiang, Yu Tao ; Yang, Yang ; Shi, Yu Zhi ; Deng, Yi Ming ; Zhu, Mei Fang ; Liu, Fei ; Yu, Ping ; Ungvari, Gabor S. ; Ng, Chee H. / The association between post-stroke depression, aphasia, and physical independence in stroke patients at 3-month follow-up. In: Frontiers in Psychiatry. 2018 ; Vol. 9, No. AUG.
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title = "The association between post-stroke depression, aphasia, and physical independence in stroke patients at 3-month follow-up",
abstract = "Objective: Few studies have examined the association between post-stroke depression (PSD), aphasia, and physical independence in Chinese patients. This study investigated the above association in stroke patients in China at 3-month follow-up. Methods: Altogether 270 patients within 14 days after ischemic stroke were recruited and followed up at 3 months. PSD, aphasia, and physical functional status were measured using the Stroke Aphasia Depression Questionnaire (SADQ), Western Aphasia Battery (WAB), and modified Rankin Scale (mRS), respectively. Patients with mRS total score > 2 were considered as having {"}physical dependence.{"} Results: Out of 248 patients at 3-month follow up, 119 (48{\%}) were rated as having physical dependence. Multiple logistic regression analyses revealed that female (p = 0.04; OR = 2.2; 95{\%} CI: 1.0-5.1), more severe stroke at admission (p < 0.01; OR = 1.4; 95{\%} CI: 1.3-1.5), and more severe PSD at 3 months (p = 0.01; OR = 1.05; 95{\%} CI: 1.01-1.1) were independently associated with physical dependence at 3 months. Conclusions: Greater PSD and stroke severity were independently associated with physical dependence at 3 months after stroke. Aphasia was also associated with physical dependence but the relationship was not significant. Early and effective depression screening, treatment and stroke rehabilitation appear to be important to improve the physical outcome and reduce the burden of stroke survivors.",
keywords = "Aphasia, Depression, Ischemic stroke, Physical independence, PSD",
author = "Shuo Wang and Wang, {Chun Xue} and Ning Zhang and Xiang, {Yu Tao} and Yang Yang and Shi, {Yu Zhi} and Deng, {Yi Ming} and Zhu, {Mei Fang} and Fei Liu and Ping Yu and Ungvari, {Gabor S.} and Ng, {Chee H.}",
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Wang, S, Wang, CX, Zhang, N, Xiang, YT, Yang, Y, Shi, YZ, Deng, YM, Zhu, MF, Liu, F, Yu, P, Ungvari, GS & Ng, CH 2018, 'The association between post-stroke depression, aphasia, and physical independence in stroke patients at 3-month follow-up' Frontiers in Psychiatry, vol. 9, no. AUG, 374. https://doi.org/10.3389/fpsyt.2018.00374

The association between post-stroke depression, aphasia, and physical independence in stroke patients at 3-month follow-up. / Wang, Shuo; Wang, Chun Xue; Zhang, Ning; Xiang, Yu Tao; Yang, Yang; Shi, Yu Zhi; Deng, Yi Ming; Zhu, Mei Fang; Liu, Fei; Yu, Ping; Ungvari, Gabor S.; Ng, Chee H.

In: Frontiers in Psychiatry, Vol. 9, No. AUG, 374, 20.08.2018.

Research output: Contribution to journalArticle

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T1 - The association between post-stroke depression, aphasia, and physical independence in stroke patients at 3-month follow-up

AU - Wang, Shuo

AU - Wang, Chun Xue

AU - Zhang, Ning

AU - Xiang, Yu Tao

AU - Yang, Yang

AU - Shi, Yu Zhi

AU - Deng, Yi Ming

AU - Zhu, Mei Fang

AU - Liu, Fei

AU - Yu, Ping

AU - Ungvari, Gabor S.

AU - Ng, Chee H.

PY - 2018/8/20

Y1 - 2018/8/20

N2 - Objective: Few studies have examined the association between post-stroke depression (PSD), aphasia, and physical independence in Chinese patients. This study investigated the above association in stroke patients in China at 3-month follow-up. Methods: Altogether 270 patients within 14 days after ischemic stroke were recruited and followed up at 3 months. PSD, aphasia, and physical functional status were measured using the Stroke Aphasia Depression Questionnaire (SADQ), Western Aphasia Battery (WAB), and modified Rankin Scale (mRS), respectively. Patients with mRS total score > 2 were considered as having "physical dependence." Results: Out of 248 patients at 3-month follow up, 119 (48%) were rated as having physical dependence. Multiple logistic regression analyses revealed that female (p = 0.04; OR = 2.2; 95% CI: 1.0-5.1), more severe stroke at admission (p < 0.01; OR = 1.4; 95% CI: 1.3-1.5), and more severe PSD at 3 months (p = 0.01; OR = 1.05; 95% CI: 1.01-1.1) were independently associated with physical dependence at 3 months. Conclusions: Greater PSD and stroke severity were independently associated with physical dependence at 3 months after stroke. Aphasia was also associated with physical dependence but the relationship was not significant. Early and effective depression screening, treatment and stroke rehabilitation appear to be important to improve the physical outcome and reduce the burden of stroke survivors.

AB - Objective: Few studies have examined the association between post-stroke depression (PSD), aphasia, and physical independence in Chinese patients. This study investigated the above association in stroke patients in China at 3-month follow-up. Methods: Altogether 270 patients within 14 days after ischemic stroke were recruited and followed up at 3 months. PSD, aphasia, and physical functional status were measured using the Stroke Aphasia Depression Questionnaire (SADQ), Western Aphasia Battery (WAB), and modified Rankin Scale (mRS), respectively. Patients with mRS total score > 2 were considered as having "physical dependence." Results: Out of 248 patients at 3-month follow up, 119 (48%) were rated as having physical dependence. Multiple logistic regression analyses revealed that female (p = 0.04; OR = 2.2; 95% CI: 1.0-5.1), more severe stroke at admission (p < 0.01; OR = 1.4; 95% CI: 1.3-1.5), and more severe PSD at 3 months (p = 0.01; OR = 1.05; 95% CI: 1.01-1.1) were independently associated with physical dependence at 3 months. Conclusions: Greater PSD and stroke severity were independently associated with physical dependence at 3 months after stroke. Aphasia was also associated with physical dependence but the relationship was not significant. Early and effective depression screening, treatment and stroke rehabilitation appear to be important to improve the physical outcome and reduce the burden of stroke survivors.

KW - Aphasia

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KW - PSD

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