The association between ambient ultraviolet radiation and/or vitamin D status and childhood-onset type 1 diabetes risk

Research output: ThesisDoctoral Thesis

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Abstract

This thesis examined the association between ambient ultraviolet radiation (UVR) and childhood-onset type 1 diabetes. Data from population-based administrative and research datasets were linked with daily erythemal UVR data from NASA satellites. Higher UVR in the last trimester of pregnancy and the first year of life was associated with reduced type 1 diabetes risk only in boys. Lower vitamin D at diagnosis was associated with greater disease severity as measured by diabetic ketoacidosis, and among boys, earlier age-of-onset. Low ambient UVR and/or vitamin D were associated with higher risk of childhood-onset type 1 diabetes risk, greater disease severity and earlier age-of-onset.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Supervisors/Advisors
  • De Klerk, Nicholas, Supervisor
  • Lucas, Robyn, Supervisor
  • Hart, Prudence, Supervisor
  • Davis, Elizabeth, Supervisor
Thesis sponsors
Award date22 Sept 2020
DOIs
Publication statusUnpublished - 2020

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