Terahertz spectroscopy of the molecular components of nucleic acids

This thesis investigates the possibility of resonant coupling between terahertz (THz) radiation and nucleoside and nucleotides in aqueous solution. THz absorption spectra were collected via THz Time-Domain Spectroscopy and Fourier Transform Infrared Spectroscopy. Spectral features were analysed and interpreted with supporting data from complementary experimental techniques such as nuclear magnetic resonance spectroscopy, Raman spectroscopy, X-ray diffraction spectroscopy, and scanning electron microscopy. The results complete a crucial gap in THz research on nucleic acids, provide further insights into the nature of THz vibrations, and points to potentially fruitful research areas for the future.