Terahertz spectroscopy of breast tumors

Philip C. Ashworth, Emma Pickwell-Macpherson, Sarah E. Pinder, Elena Provenzano, Anand D. Purushotham, Michael Pepper, Vincent P. Wallace

Research output: Chapter in Book/Conference paperConference paper

10 Citations (Scopus)

Abstract

Using a portable terahertz pulsed spectrometer developed by TeraView Ltd. the complex refractive indices of ex vivo breast tumors were measured through transmission in the range of 0.1 - 3 THz. Twenty samples were measured at room temperature and it is shown here that the use of terahertz pulsed spectroscopy (TPS) enables us to distinguish between normal adipose tissue, normal fibrous tissue and breast tumors due to the higher water content and structural differences found in tumors. Comparisons are made between the results found using TPS and the classification of the tissue samples given through histology performed at Addenbrooke's Hospital, Cambridge. Further measurements have been taken at low temperatures (down to 200K) to remove the dominant absorption caused by water in an attempt to identify other differences, such as the cell and protein density, between normal breast tissue and tumors observable in the THz range.

Original languageEnglish
Title of host publicationIRMMW-THz2007 - Conference Digest of the Joint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics
Pages603-605
Number of pages3
Publication statusPublished - 2007
Externally publishedYes
EventJoint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics, IRMMW-THz2007 - Cardiff, United Kingdom
Duration: 3 Sep 20077 Sep 2007

Conference

ConferenceJoint 32nd International Conference on Infrared and Millimetre Waves, and 15th International Conference on Terahertz Electronics, IRMMW-THz2007
CountryUnited Kingdom
CityCardiff
Period3/09/077/09/07

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