Terahertz Pulsed Imaging of liver cirrhosis

Shengyang Huang; Yi xiang Wang; Jun Yu; Anil T. Ahuja; Vincent P. Wallace; Yuan Ting Zhang; Emma Pickwell-Macpherson

doi:10.1109/ICIMW.2009.5324758

Terahertz Pulsed Imaging of liver cirrhosis

Shengyang Huang
, Yi xiang Wang
, Jun Yu
, Anil T. Ahuja
, Vincent P. Wallace
, Yuan Ting Zhang
, Emma Pickwell-Macpherson

Research output: Chapter in Book/Conference paper › Conference paper › peer-review

3 Citations (Scopus)

Abstract

Terahertz Pulsed Imaging (TPI™) is a coherent imaging technique that can be used to reveal the dielectric properties of samples. Liver cirrhosis is a common disease that can lead to hepatocellular carcinoma. It has been previously studied in the microwave region and the dielectric parameters of human cirrhotic liver were quantified. In this study, we characterized the refractive index and absorption coefficient of cirrhotic and normal liver tissue from laboratory rats in the terahertz region using TPI. We observed that both the refractive index and absorption coefficient of the cirrhotic liver samples were consistently higher than those of the normal samples from 0.2 to 1.5 THz. After the samples were fixed in formalin solution for 24 hours, differences in the refractive index and absorption coefficient were still seen. These results illustrate the sensitivity of TPI to soft tissue and provide motivation for developing TPI into a clinical imaging technique.

Original language	English
Title of host publication	34th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2009
DOIs	https://doi.org/10.1109/ICIMW.2009.5324758
Publication status	Published - 2009
Event	34th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2009 - Busan, Korea, Republic of Duration: 21 Sept 2009 → 25 Sept 2009

Conference

Conference	34th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2009
Country/Territory	Korea, Republic of
City	Busan
Period	21/09/09 → 25/09/09

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1109/ICIMW.2009.5324758

Cite this

@inproceedings{d62f7cacf066497286d049488c01ab5a,

title = "Terahertz Pulsed Imaging of liver cirrhosis",

abstract = "Terahertz Pulsed Imaging (TPI{\texttrademark}) is a coherent imaging technique that can be used to reveal the dielectric properties of samples. Liver cirrhosis is a common disease that can lead to hepatocellular carcinoma. It has been previously studied in the microwave region and the dielectric parameters of human cirrhotic liver were quantified. In this study, we characterized the refractive index and absorption coefficient of cirrhotic and normal liver tissue from laboratory rats in the terahertz region using TPI. We observed that both the refractive index and absorption coefficient of the cirrhotic liver samples were consistently higher than those of the normal samples from 0.2 to 1.5 THz. After the samples were fixed in formalin solution for 24 hours, differences in the refractive index and absorption coefficient were still seen. These results illustrate the sensitivity of TPI to soft tissue and provide motivation for developing TPI into a clinical imaging technique.",

author = "Shengyang Huang and Wang, \{Yi xiang\} and Jun Yu and Ahuja, \{Anil T.\} and Wallace, \{Vincent P.\} and Zhang, \{Yuan Ting\} and Emma Pickwell-Macpherson",

year = "2009",

doi = "10.1109/ICIMW.2009.5324758",

language = "English",

isbn = "9781424454174",

booktitle = "34th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2009",

note = "34th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2009 ; Conference date: 21-09-2009 Through 25-09-2009",

}

Huang, S, Wang, YX, Yu, J, Ahuja, AT, Wallace, VP, Zhang, YT & Pickwell-Macpherson, E 2009, Terahertz Pulsed Imaging of liver cirrhosis. in 34th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2009., 5324758, 34th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2009, Busan, Korea, Republic of, 21/09/09. https://doi.org/10.1109/ICIMW.2009.5324758

TY - GEN

T1 - Terahertz Pulsed Imaging of liver cirrhosis

AU - Huang, Shengyang

AU - Wang, Yi xiang

AU - Yu, Jun

AU - Ahuja, Anil T.

AU - Wallace, Vincent P.

AU - Zhang, Yuan Ting

AU - Pickwell-Macpherson, Emma

PY - 2009

Y1 - 2009

N2 - Terahertz Pulsed Imaging (TPI™) is a coherent imaging technique that can be used to reveal the dielectric properties of samples. Liver cirrhosis is a common disease that can lead to hepatocellular carcinoma. It has been previously studied in the microwave region and the dielectric parameters of human cirrhotic liver were quantified. In this study, we characterized the refractive index and absorption coefficient of cirrhotic and normal liver tissue from laboratory rats in the terahertz region using TPI. We observed that both the refractive index and absorption coefficient of the cirrhotic liver samples were consistently higher than those of the normal samples from 0.2 to 1.5 THz. After the samples were fixed in formalin solution for 24 hours, differences in the refractive index and absorption coefficient were still seen. These results illustrate the sensitivity of TPI to soft tissue and provide motivation for developing TPI into a clinical imaging technique.

AB - Terahertz Pulsed Imaging (TPI™) is a coherent imaging technique that can be used to reveal the dielectric properties of samples. Liver cirrhosis is a common disease that can lead to hepatocellular carcinoma. It has been previously studied in the microwave region and the dielectric parameters of human cirrhotic liver were quantified. In this study, we characterized the refractive index and absorption coefficient of cirrhotic and normal liver tissue from laboratory rats in the terahertz region using TPI. We observed that both the refractive index and absorption coefficient of the cirrhotic liver samples were consistently higher than those of the normal samples from 0.2 to 1.5 THz. After the samples were fixed in formalin solution for 24 hours, differences in the refractive index and absorption coefficient were still seen. These results illustrate the sensitivity of TPI to soft tissue and provide motivation for developing TPI into a clinical imaging technique.

UR - https://www.scopus.com/pages/publications/72749087072

U2 - 10.1109/ICIMW.2009.5324758

DO - 10.1109/ICIMW.2009.5324758

M3 - Conference paper

AN - SCOPUS:72749087072

SN - 9781424454174

BT - 34th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2009

T2 - 34th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2009

Y2 - 21 September 2009 through 25 September 2009

ER -

Terahertz Pulsed Imaging of liver cirrhosis

Abstract

Conference

UN SDGs

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