Tectal Tissue Grafted to the Midbrain of Newborn Rats: Effect of Donor Age on the Survival, Growth and Connectivity of Transplants

Bernadette T. Majda, Alan R. Harvey

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Tectal tissue from fetal (E15, E18, E20) and newborn (PO) rats was transplanted to the midbrain of newborn rats. Graft survival and size decreased with increasing donor age. Host retinal input was found in E15, E18 and E20 grafts; the specific pattern of retinal innervation was similar for all fetal donor ages.

Original languageEnglish
Pages (from-to)95-103
Number of pages9
JournalJournal of Neural Transplantation
Volume1
Issue number3-4
DOIs
Publication statusPublished - 1 Jan 1989
Externally publishedYes

Fingerprint

Mesencephalon
Transplants
Graft Survival
Growth
Gestational Age
Fetus

Cite this

@article{66495931771b43f799ce8011766b909e,
title = "Tectal Tissue Grafted to the Midbrain of Newborn Rats: Effect of Donor Age on the Survival, Growth and Connectivity of Transplants",
abstract = "Tectal tissue from fetal (E15, E18, E20) and newborn (PO) rats was transplanted to the midbrain of newborn rats. Graft survival and size decreased with increasing donor age. Host retinal input was found in E15, E18 and E20 grafts; the specific pattern of retinal innervation was similar for all fetal donor ages.",
keywords = "cell death, donor age, neural transplants, retinotectal projections, Superior colliculus, target specificity",
author = "Majda, {Bernadette T.} and Harvey, {Alan R.}",
year = "1989",
month = "1",
day = "1",
doi = "10.1155/NP.1989.95",
language = "English",
volume = "1",
pages = "95--103",
journal = "Journal of Neural Transplantation",
issn = "1352-237X",
publisher = "Hindawi Publishing Corporation",
number = "3-4",

}

TY - JOUR

T1 - Tectal Tissue Grafted to the Midbrain of Newborn Rats

T2 - Effect of Donor Age on the Survival, Growth and Connectivity of Transplants

AU - Majda, Bernadette T.

AU - Harvey, Alan R.

PY - 1989/1/1

Y1 - 1989/1/1

N2 - Tectal tissue from fetal (E15, E18, E20) and newborn (PO) rats was transplanted to the midbrain of newborn rats. Graft survival and size decreased with increasing donor age. Host retinal input was found in E15, E18 and E20 grafts; the specific pattern of retinal innervation was similar for all fetal donor ages.

AB - Tectal tissue from fetal (E15, E18, E20) and newborn (PO) rats was transplanted to the midbrain of newborn rats. Graft survival and size decreased with increasing donor age. Host retinal input was found in E15, E18 and E20 grafts; the specific pattern of retinal innervation was similar for all fetal donor ages.

KW - cell death

KW - donor age

KW - neural transplants

KW - retinotectal projections

KW - Superior colliculus

KW - target specificity

UR - http://www.scopus.com/inward/record.url?scp=0024794218&partnerID=8YFLogxK

U2 - 10.1155/NP.1989.95

DO - 10.1155/NP.1989.95

M3 - Article

VL - 1

SP - 95

EP - 103

JO - Journal of Neural Transplantation

JF - Journal of Neural Transplantation

SN - 1352-237X

IS - 3-4

ER -