Projects per year
Abstract
A pangenome captures the genomic diversity for a species, derived from a collection of genetic sequences of diverse populations. Advances in sequencing technologies have given rise to three primary methods for pangenome construction and analysis: de novo assembly and comparison, reference genome-based iterative assembly, and graph-based pangenome construction. Each method presents advantages and challenges in processing varying amounts and structures of DNA sequencing data. With the emergence of high-quality genome assemblies and advanced bioinformatic tools, the graph-based pangenome is emerging as an advanced reference for exploring the biological and functional implications of genetic variations.
Original language | English |
---|---|
Article number | evae081 |
Number of pages | 9 |
Journal | Genome Biology and Evolution |
Volume | 16 |
Issue number | 4 |
DOIs | |
Publication status | Published - Apr 2024 |
Fingerprint
Dive into the research topics of 'Technological Development and Advances for Constructing and Analyzing Plant Pangenomes'. Together they form a unique fingerprint.-
Who’s who in the plant gene world?
ARC Australian Research Council
1/01/20 → 31/12/24
Project: Research
-
Understanding disease resistance gene evolution across the Brassicaceae
ARC Australian Research Council
1/06/21 → 30/06/24
Project: Research