Targeting osteoclasts for treatment of high-risk B-cell acute lymphoblastic leukemia

Rishi S. Kotecha; Sarah M. Trinder; Anastasia M. Hughes; Benjamin H. Mullin; Sarah Rashid; Jinbo Yuan; Jiake Xu; Owen Duncan; Patrycja Skut; Grace Alyssa Chua; Sajla Singh; Joyce Oommen; Richard B. Lock; Ursula R. Kees; Sebastien Malinge; Vincent Kuek; Laurence C. Cheung

doi:10.1038/s41408-025-01239-3

Targeting osteoclasts for treatment of high-risk B-cell acute lymphoblastic leukemia

Rishi S. Kotecha, Sarah M. Trinder, Anastasia M. Hughes, Benjamin H. Mullin, Sarah Rashid, Jinbo Yuan, Jiake Xu, Owen Duncan, Patrycja Skut, Grace Alyssa Chua, Sajla Singh, Joyce Oommen, Richard B. Lock, Ursula R. Kees, Sebastien Malinge, Vincent Kuek, Laurence C. Cheung

Research output: Contribution to journal › Letter › peer-review

Original language	English
Article number	25
Number of pages	5
Journal	Blood Cancer Journal
Volume	15
Issue number	1
Early online date	27 Feb 2025
DOIs	https://doi.org/10.1038/s41408-025-01239-3
Publication status	E-pub ahead of print - 27 Feb 2025

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10.1038/s41408-025-01239-3Licence: CC BY

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Kotecha, R. S., Trinder, S. M., Hughes, A. M., Mullin, B. H., Rashid, S., Yuan, J., Xu, J., Duncan, O., Skut, P., Chua, G. A., Singh, S., Oommen, J., Lock, R. B., Kees, U. R., Malinge, S., Kuek, V., & Cheung, L. C. (2025). Targeting osteoclasts for treatment of high-risk B-cell acute lymphoblastic leukemia. Blood Cancer Journal, 15(1), Article 25. Advance online publication. https://doi.org/10.1038/s41408-025-01239-3

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title = "Targeting osteoclasts for treatment of high-risk B-cell acute lymphoblastic leukemia",

author = "Kotecha, {Rishi S.} and Trinder, {Sarah M.} and Hughes, {Anastasia M.} and Mullin, {Benjamin H.} and Sarah Rashid and Jinbo Yuan and Jiake Xu and Owen Duncan and Patrycja Skut and Chua, {Grace Alyssa} and Sajla Singh and Joyce Oommen and Lock, {Richard B.} and Kees, {Ursula R.} and Sebastien Malinge and Vincent Kuek and Cheung, {Laurence C.}",

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T1 - Targeting osteoclasts for treatment of high-risk B-cell acute lymphoblastic leukemia

AU - Kotecha, Rishi S.

AU - Trinder, Sarah M.

AU - Hughes, Anastasia M.

AU - Mullin, Benjamin H.

AU - Rashid, Sarah

AU - Yuan, Jinbo

AU - Xu, Jiake

AU - Duncan, Owen

AU - Skut, Patrycja

AU - Chua, Grace Alyssa

AU - Singh, Sajla

AU - Oommen, Joyce

AU - Lock, Richard B.

AU - Kees, Ursula R.

AU - Malinge, Sebastien

AU - Kuek, Vincent

AU - Cheung, Laurence C.

PY - 2025/2/27

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U2 - 10.1038/s41408-025-01239-3

DO - 10.1038/s41408-025-01239-3

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JO - Blood Cancer Journal

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Targeting osteoclasts for treatment of high-risk B-cell acute lymphoblastic leukemia

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Targeting osteoclasts for treatment of high-risk B-cell acute lymphoblastic leukemia

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Analysis of the osteoclast methylome for characterisation of epigenetic mechanisms underlying metabolic bone disease

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