TAK-475 - an oral inhibitor of squalene synthase for hyperlipidemia

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    Abstract

    Takeda Pharmaceutical Co Ltd is developing TAK-475, a squalene synthetase inhibitor from a series of 4,1-benzoxazepine-3-acetic acid derivatives, for the potential oral treatment of hyperlipidemia. By March 2005, TAK-475 was undergoing phase III clinical trials in the US and Europe.
    Original languageEnglish
    Pages (from-to)850-856
    JournalCurrent Opinion in Investigational Drugs
    Volume7
    Issue number9
    Publication statusPublished - 2006

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