Hyaline-vascular Castleman disease (HVCD) often presents as unicentric disease which is usually cured by surgical resection. Here, we report a case of a 23-year-old man with HVCD in the mediastinum, in which an apparently indolent T-lymphoblastic proliferation and extensive organoid proliferation of follicular dendritic cells were also present. The patient had no systemic involvement and no further disease at follow-up. In addition, there is a possible unique family history of HVCD. This case highlights an interesting combination of elements, mostly likely benign in nature. © 2013 Springer-Verlag Berlin Heidelberg.
Leslie, C., Shingde, M. V., Kwok, F., Platten, M. A., Tesfai, Y., Amanuel, B., & Spagnolo, D. (2013). T-lymphoblastic proliferation and florid multifocal follicular dendritic cell proliferation occurring in hyaline-vascular Castleman disease in a patient with a possible familial predisposition. Journal of Hematopathology, 6(4), 237-244. https://doi.org/10.1007/s12308-013-0184-x