Synthesizing cellular networks from evolved ribosome-mRNA pairs

O Rackham, Jason Chin

Research output: Contribution to journalArticle

11 Citations (Scopus)


We describe cellular engineering for the creation of multiple new cellular modules each composed of an orthogonal ribosome and orthogonal mRNA. These modules operate independently of the endogenous ribosome and mRNA. We discuss some of the applications of orthogonal pairs and highlight the expression of Boolean logic in gene regulation using multiple orthogonal pairs.

Original languageEnglish
Pages (from-to)328-9
Number of pages2
JournalBiochemical Society Transactions
Issue numberPt 2
Publication statusPublished - Apr 2006
Externally publishedYes

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