This letter focuses on the first result the preparation and its swelling behavior of a novel hybrid gelatin hydrogel with carbon nanotubes.A novel hybrid gelatin hydrogel with carbon nanotubes was synthesized by physical mixing method. The structure of the novel hydorgelobtained was characterized by SEM. Besides, the swelling behavior of the hydrogel synthesized was measured at different temperature. Theresults indicated that carbon nanotubes added could maintain the stability of the hybrid hydrogel at 37 ◦C. This suggests that the hybrid gelatinhydrogel with carbon nanotubes could be used in biomedical field. Besides, its application in protein concentrating has been discussed.© 2003 Elsevier B.V. All rights reserved.