Synthesis of 1,3,4-Oxadiazoles via Annulation of Hydrazides and Benzene-1,3,5-triyl Triformate under Metal-Free Conditions

Z. Yin, D. J. Power, Z. Wang, S.G. Stewart, X.F. Wu

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

A new and efficient method for the synthesis of 1,3,4-oxadiazoles via the annulation of hydrazides with benzene-1,3,5-triyl triformate (TFBen) under metal-free conditions is reported. A broad range of hydrazides were transformed into the corresponding 1,3,4-oxadiazoles in good yields with excellent functional group tolerance.

Original languageEnglish
Pages (from-to)3238-3242
Number of pages5
JournalSynthesis (Germany)
Volume50
Issue number16
DOIs
Publication statusPublished - 16 Apr 2018

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