Synthesis of 1,3,4-Oxadiazoles via Annulation of Hydrazides and Benzene-1,3,5-triyl Triformate under Metal-Free Conditions

Z. Yin, D. J. Power, Z. Wang, S.G. Stewart, X.F. Wu

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A new and efficient method for the synthesis of 1,3,4-oxadiazoles via the annulation of hydrazides with benzene-1,3,5-triyl triformate (TFBen) under metal-free conditions is reported. A broad range of hydrazides were transformed into the corresponding 1,3,4-oxadiazoles in good yields with excellent functional group tolerance.

Original languageEnglish
Pages (from-to)3238-3242
JournalSynthesis (Germany)
Volume50
Issue number16
DOIs
Publication statusPublished - 16 Apr 2018

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Benzene
Functional groups
Metals
1,3,4-oxadiazole

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title = "Synthesis of 1,3,4-Oxadiazoles via Annulation of Hydrazides and Benzene-1,3,5-triyl Triformate under Metal-Free Conditions",
abstract = "A new and efficient method for the synthesis of 1,3,4-oxadiazoles via the annulation of hydrazides with benzene-1,3,5-triyl triformate (TFBen) under metal-free conditions is reported. A broad range of hydrazides were transformed into the corresponding 1,3,4-oxadiazoles in good yields with excellent functional group tolerance.",
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Synthesis of 1,3,4-Oxadiazoles via Annulation of Hydrazides and Benzene-1,3,5-triyl Triformate under Metal-Free Conditions. / Yin, Z.; Power, D. J.; Wang, Z.; Stewart, S.G.; Wu, X.F.

In: Synthesis (Germany), Vol. 50, No. 16, 16.04.2018, p. 3238-3242.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Synthesis of 1,3,4-Oxadiazoles via Annulation of Hydrazides and Benzene-1,3,5-triyl Triformate under Metal-Free Conditions

AU - Yin, Z.

AU - Power, D. J.

AU - Wang, Z.

AU - Stewart, S.G.

AU - Wu, X.F.

PY - 2018/4/16

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KW - carbonylation

KW - cyclisation

KW - formates

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