Synthesis and X-ray crystal structure of 8,9-dimethoxy-4-methyl-3-phenyl-2,3,5,6-tetrahydropyrrolo[2,1-a]isoquinolinium iodide

T.S. Bailey, J.B. Bremner, L. Pelosi, Brian Skelton, Allan White

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2 Citations (Scopus)

Abstract

N-Methylation of 6,7-dimethoxy-1-(2'-phenylcyclopropyl)-3,4-dihydroisoquinoline (3b) with iodomethane in refluxing acetone gave the modified Cloke rearrangement product, 8,9-dimethoxy-4-methyl-3-phenyl-2,3,5,6-tetrahyropyrrolo [2,1-a]isoquinolinium iodide (5b), a new derivative of the pyrrolo[2,1-a]isoquinoline skeleton, together with the methiodide salt (4b) of (3b). The structure of (5b) was confirmed by X-ray crystallographic analysis.
Original languageEnglish
Pages (from-to)1437-1445
JournalAustralian Journal of Chemistry: an international journal for chemical science
Volume48
DOIs
Publication statusPublished - 1995

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