Synchronous Multifocal Canalicular Adenomas

Ahmed S. Sultan; Frank S.C. Chang; Tom Cooper; Maryam Jessri

doi:10.1007/s12105-021-01293-w

Synchronous Multifocal Canalicular Adenomas

Ahmed S. Sultan
, Frank S.C. Chang
, Tom Cooper
, Maryam Jessri

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Canalicular adenoma (CAD) is an uncommon benign tumor of minor salivary glands with predilection for the upper labial mucosa. An 80-year-old female presented with nine submucosal nodules of the upper labial mucosa and bilateral buccal mucosa. Histopathologic examination revealed multifocal circumscribed tumor islands with a tubular growth pattern within a loose hypocellular myxoid background stroma. Interconnecting rows of columnar tumor cells imparted a canalicular morphology. In addition to the characteristic histopathologic findings, a comprehensive immunohistochemical panel supported a final diagnosis of multifocal CAD. Synchronous multifocality in CAD is an infrequent finding and this sine qua non clinicopathologic correlation article exemplifies such a case.

Original language	English
Pages (from-to)	945-949
Number of pages	5
Journal	Head and Neck Pathology
Volume	15
Issue number	3
DOIs	https://doi.org/10.1007/s12105-021-01293-w
Publication status	Published - Sept 2021
Externally published	Yes

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10.1007/s12105-021-01293-w

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385040

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title = "Synchronous Multifocal Canalicular Adenomas",

abstract = "Canalicular adenoma (CAD) is an uncommon benign tumor of minor salivary glands with predilection for the upper labial mucosa. An 80-year-old female presented with nine submucosal nodules of the upper labial mucosa and bilateral buccal mucosa. Histopathologic examination revealed multifocal circumscribed tumor islands with a tubular growth pattern within a loose hypocellular myxoid background stroma. Interconnecting rows of columnar tumor cells imparted a canalicular morphology. In addition to the characteristic histopathologic findings, a comprehensive immunohistochemical panel supported a final diagnosis of multifocal CAD. Synchronous multifocality in CAD is an infrequent finding and this sine qua non clinicopathologic correlation article exemplifies such a case.",

keywords = "Benign salivary gland tumour, Minor salivary glands, Multifocal canalicular adenoma",

author = "Sultan, \{Ahmed S.\} and Chang, \{Frank S.C.\} and Tom Cooper and Maryam Jessri",

year = "2021",

month = sep,

doi = "10.1007/s12105-021-01293-w",

language = "English",

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pages = "945--949",

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TY - JOUR

T1 - Synchronous Multifocal Canalicular Adenomas

AU - Sultan, Ahmed S.

AU - Chang, Frank S.C.

AU - Cooper, Tom

AU - Jessri, Maryam

PY - 2021/9

Y1 - 2021/9

N2 - Canalicular adenoma (CAD) is an uncommon benign tumor of minor salivary glands with predilection for the upper labial mucosa. An 80-year-old female presented with nine submucosal nodules of the upper labial mucosa and bilateral buccal mucosa. Histopathologic examination revealed multifocal circumscribed tumor islands with a tubular growth pattern within a loose hypocellular myxoid background stroma. Interconnecting rows of columnar tumor cells imparted a canalicular morphology. In addition to the characteristic histopathologic findings, a comprehensive immunohistochemical panel supported a final diagnosis of multifocal CAD. Synchronous multifocality in CAD is an infrequent finding and this sine qua non clinicopathologic correlation article exemplifies such a case.

AB - Canalicular adenoma (CAD) is an uncommon benign tumor of minor salivary glands with predilection for the upper labial mucosa. An 80-year-old female presented with nine submucosal nodules of the upper labial mucosa and bilateral buccal mucosa. Histopathologic examination revealed multifocal circumscribed tumor islands with a tubular growth pattern within a loose hypocellular myxoid background stroma. Interconnecting rows of columnar tumor cells imparted a canalicular morphology. In addition to the characteristic histopathologic findings, a comprehensive immunohistochemical panel supported a final diagnosis of multifocal CAD. Synchronous multifocality in CAD is an infrequent finding and this sine qua non clinicopathologic correlation article exemplifies such a case.

KW - Benign salivary gland tumour

KW - Minor salivary glands

KW - Multifocal canalicular adenoma

UR - https://www.scopus.com/pages/publications/85100533846

U2 - 10.1007/s12105-021-01293-w

DO - 10.1007/s12105-021-01293-w

M3 - Article

C2 - 33544378

AN - SCOPUS:85100533846

SN - 1936-055X

VL - 15

SP - 945

EP - 949

JO - Head and Neck Pathology

JF - Head and Neck Pathology

IS - 3

ER -

Synchronous Multifocal Canalicular Adenomas

Abstract

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