Synchronous Multifocal Canalicular Adenomas

Ahmed S. Sultan, Frank S.C. Chang, Tom Cooper, Maryam Jessri

Research output: Contribution to journalArticlepeer-review


Canalicular adenoma (CAD) is an uncommon benign tumor of minor salivary glands with predilection for the upper labial mucosa. An 80-year-old female presented with nine submucosal nodules of the upper labial mucosa and bilateral buccal mucosa. Histopathologic examination revealed multifocal circumscribed tumor islands with a tubular growth pattern within a loose hypocellular myxoid background stroma. Interconnecting rows of columnar tumor cells imparted a canalicular morphology. In addition to the characteristic histopathologic findings, a comprehensive immunohistochemical panel supported a final diagnosis of multifocal CAD. Synchronous multifocality in CAD is an infrequent finding and this sine qua non clinicopathologic correlation article exemplifies such a case.

Original languageEnglish
Pages (from-to)945-949
JournalHead and Neck Pathology
Issue number3
Publication statusPublished - Sep 2021
Externally publishedYes


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