Synacthen Depot® for the treatment of postdural puncture headache

M.W.M. Rucklidge; S.M. Yentis; Mike Paech

doi:10.1111/j.1365-2044.2004.03573.x

Synacthen Depot® for the treatment of postdural puncture headache

M.W.M. Rucklidge, S.M. Yentis, Mike Paech

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36 Citations (Scopus)

Abstract

We conducted a prospective, randomised, double-blind trial to study the effect of Synacthen Depot® in 18 parturients with postdural puncture headache following deliberate or accidental dural puncture. Women were randomly allocated to receive either Synacthen Depot 1 mg (1 ml) or 0.9% saline 1 ml intramuscularly. Using a 10-cm visual analogue scale, severity of headache was measured before and at intervals until 48 h after injection. There was no difference in the severity of headache or requirement for epidural blood patch. We conclude that there is no advantage to the use of Synacthen Depot 1 mg for the treatment of postdural puncture headache.

Original language	English
Pages (from-to)	138-141
Journal	Anaesthesia
Volume	59
Issue number	2
DOIs	https://doi.org/10.1111/j.1365-2044.2004.03573.x
Publication status	Published - 2004

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title = "Synacthen Depot{\textregistered} for the treatment of postdural puncture headache",

abstract = "We conducted a prospective, randomised, double-blind trial to study the effect of Synacthen Depot{\textregistered} in 18 parturients with postdural puncture headache following deliberate or accidental dural puncture. Women were randomly allocated to receive either Synacthen Depot 1 mg (1 ml) or 0.9% saline 1 ml intramuscularly. Using a 10-cm visual analogue scale, severity of headache was measured before and at intervals until 48 h after injection. There was no difference in the severity of headache or requirement for epidural blood patch. We conclude that there is no advantage to the use of Synacthen Depot 1 mg for the treatment of postdural puncture headache.",

author = "M.W.M. Rucklidge and S.M. Yentis and Mike Paech",

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AU - Rucklidge, M.W.M.

AU - Yentis, S.M.

AU - Paech, Mike

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Y1 - 2004

N2 - We conducted a prospective, randomised, double-blind trial to study the effect of Synacthen Depot® in 18 parturients with postdural puncture headache following deliberate or accidental dural puncture. Women were randomly allocated to receive either Synacthen Depot 1 mg (1 ml) or 0.9% saline 1 ml intramuscularly. Using a 10-cm visual analogue scale, severity of headache was measured before and at intervals until 48 h after injection. There was no difference in the severity of headache or requirement for epidural blood patch. We conclude that there is no advantage to the use of Synacthen Depot 1 mg for the treatment of postdural puncture headache.

AB - We conducted a prospective, randomised, double-blind trial to study the effect of Synacthen Depot® in 18 parturients with postdural puncture headache following deliberate or accidental dural puncture. Women were randomly allocated to receive either Synacthen Depot 1 mg (1 ml) or 0.9% saline 1 ml intramuscularly. Using a 10-cm visual analogue scale, severity of headache was measured before and at intervals until 48 h after injection. There was no difference in the severity of headache or requirement for epidural blood patch. We conclude that there is no advantage to the use of Synacthen Depot 1 mg for the treatment of postdural puncture headache.

U2 - 10.1111/j.1365-2044.2004.03573.x

DO - 10.1111/j.1365-2044.2004.03573.x

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VL - 59

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EP - 141

JO - Anaesthesia

JF - Anaesthesia

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ER -

Synacthen Depot® for the treatment of postdural puncture headache

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