Synacthen Depot® for the treatment of postdural puncture headache

M.W.M. Rucklidge, S.M. Yentis, Mike Paech

    Research output: Contribution to journalArticlepeer-review

    32 Citations (Scopus)


    We conducted a prospective, randomised, double-blind trial to study the effect of Synacthen Depot® in 18 parturients with postdural puncture headache following deliberate or accidental dural puncture. Women were randomly allocated to receive either Synacthen Depot 1 mg (1 ml) or 0.9% saline 1 ml intramuscularly. Using a 10-cm visual analogue scale, severity of headache was measured before and at intervals until 48 h after injection. There was no difference in the severity of headache or requirement for epidural blood patch. We conclude that there is no advantage to the use of Synacthen Depot 1 mg for the treatment of postdural puncture headache.
    Original languageEnglish
    Pages (from-to)138-141
    Issue number2
    Publication statusPublished - 2004


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