TY - JOUR
T1 - Subjective cognitive decline disrupts aspects of prospective memory in older adults with HIV disease
AU - Thompson, Jennifer L.
AU - Sheppard, David P.
AU - Matchanova, Anastasia
AU - Morgan, Erin E.
AU - Loft, Shayne
AU - Woods, Steven Paul
PY - 2023
Y1 - 2023
N2 - Subjective cognitive decline (SCD) is a risk factor for dementia that may occur at higher rates in people with HIV (PWH). Prospective memory (PM) is an aspect of cognition that may help us better understand how SCD impacts daily life. Paricipants were 62 PWH aged ≥ 50 years and 33 seronegative individuals. SCD was operationalized as normatively elevated cognitive symptoms on standardized questionnaires, but with normatively unimpaired performance-based cognition and no current affective disorders. PM was measured with the Comprehensive Assessment of Prospective Memory (CAPM), the Cambridge Test of Prospective Memory (CAMPROMPT), and an experimental computerized time-based PM task. A logistic regression revealed that older PWH had a three-fold increased likelihood for SCD. Among the PWH, SCD was associated with more frequent PM symptoms and poorer accuracy on the time-based scale of the CAMPROMPT. These findings suggest that SCD disrupts PM in older PWH.
AB - Subjective cognitive decline (SCD) is a risk factor for dementia that may occur at higher rates in people with HIV (PWH). Prospective memory (PM) is an aspect of cognition that may help us better understand how SCD impacts daily life. Paricipants were 62 PWH aged ≥ 50 years and 33 seronegative individuals. SCD was operationalized as normatively elevated cognitive symptoms on standardized questionnaires, but with normatively unimpaired performance-based cognition and no current affective disorders. PM was measured with the Comprehensive Assessment of Prospective Memory (CAPM), the Cambridge Test of Prospective Memory (CAMPROMPT), and an experimental computerized time-based PM task. A logistic regression revealed that older PWH had a three-fold increased likelihood for SCD. Among the PWH, SCD was associated with more frequent PM symptoms and poorer accuracy on the time-based scale of the CAMPROMPT. These findings suggest that SCD disrupts PM in older PWH.
KW - Aging
KW - everyday functioning
KW - future thinking
KW - infectious disease
KW - neuropsychological assessment
KW - subjective cognitive impairment
UR - http://www.scopus.com/inward/record.url?scp=85129125261&partnerID=8YFLogxK
M3 - Article
C2 - 35412440
AN - SCOPUS:85129125261
SN - 1382-5585
VL - 30
SP - 582
EP - 600
JO - Aging, Neuropsychology, and Cognition
JF - Aging, Neuropsychology, and Cognition
IS - 4
ER -
