Subject-specific non-linear biomechanical model of needle insertion into brain

Adam Wittek, T. Dutta Roy, Z.A. Taylor, A.T. Horton, T. Washio, K. Chinzei, Karol Miller

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The previous models for predicting the forces acting on a needle during insertion into very soft organs (such as, e.g. brain) relied on oversimplifying assumptions of linear elasticity and specific experimentally derived functions for determining needle-tissue interactions. In this contribution, we propose a more general approach in which the needle forces are determined directly from the equations of continuum mechanics using fully non-linear finite element procedures that account for large deformations (geometric non-linearity) and non-linear stress-strain relationship (material non-linearity) of soft tissues. We applied these procedures to model needle insertion into a swine brain using the constitutive properties determined from the experiments on tissue samples obtained from the same brain (i.e. the subject-specific constitutive properties were used). We focused on the insertion phase preceding puncture of the brain meninges and obtained a very accurate prediction of the needle force. This demonstrates the utility of non-linear finite element procedures in patient-specific modelling of needle insertion into soft organs such as, e.g. brain.
Original languageEnglish
Pages (from-to)135-146
JournalComputer Methods in Biomechanics and Biomedical Engineering
Volume11
Issue number2
DOIs
Publication statusPublished - 2008

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