Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers

Joseph H Kado; Sam Salman; Robert Henderson; Robert Hand; Rosemary Wyber; Madhu Page-Sharp; Kevin Batty; Jonathan Carapetis; Laurens Manning

doi:10.1093/jac/dkaa282

Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers

Joseph H Kado
, Sam Salman
, Robert Henderson
, Robert Hand
, Rosemary Wyber
, Madhu Page-Sharp
, Kevin Batty
, Jonathan Carapetis
, Laurens Manning

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	2951-2959
Number of pages	9
Journal	Journal of Antimicrobial Chemotherapy
Volume	75
Issue number	10
Early online date	22 Jul 2020
DOIs	https://doi.org/10.1093/jac/dkaa282
Publication status	Published - 1 Oct 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1093/jac/dkaa282

Cite this

Kado, J. H., Salman, S., Henderson, R., Hand, R., Wyber, R., Page-Sharp, M., Batty, K., Carapetis, J., & Manning, L. (2020). Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers. Journal of Antimicrobial Chemotherapy, 75(10), 2951-2959. https://doi.org/10.1093/jac/dkaa282

Kado, Joseph H ; Salman, Sam ; Henderson, Robert et al. / Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection : a randomized, crossover, population pharmacokinetic study in healthy adult volunteers. In: Journal of Antimicrobial Chemotherapy. 2020 ; Vol. 75, No. 10. pp. 2951-2959.

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title = "Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers",

author = "Kado, \{Joseph H\} and Sam Salman and Robert Henderson and Robert Hand and Rosemary Wyber and Madhu Page-Sharp and Kevin Batty and Jonathan Carapetis and Laurens Manning",

year = "2020",

month = oct,

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Kado, JH, Salman, S, Henderson, R, Hand, R, Wyber, R, Page-Sharp, M, Batty, K, Carapetis, J & Manning, L 2020, 'Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers', Journal of Antimicrobial Chemotherapy, vol. 75, no. 10, pp. 2951-2959. https://doi.org/10.1093/jac/dkaa282

Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers. / Kado, Joseph H; Salman, Sam; Henderson, Robert et al.
In: Journal of Antimicrobial Chemotherapy, Vol. 75, No. 10, 01.10.2020, p. 2951-2959.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection

T2 - a randomized, crossover, population pharmacokinetic study in healthy adult volunteers

AU - Kado, Joseph H

AU - Salman, Sam

AU - Henderson, Robert

AU - Hand, Robert

AU - Wyber, Rosemary

AU - Page-Sharp, Madhu

AU - Batty, Kevin

AU - Carapetis, Jonathan

AU - Manning, Laurens

PY - 2020/10/1

Y1 - 2020/10/1

UR - https://www.scopus.com/pages/publications/85091324983

U2 - 10.1093/jac/dkaa282

DO - 10.1093/jac/dkaa282

M3 - Article

C2 - 32696033

SN - 0305-7453

VL - 75

SP - 2951

EP - 2959

JO - Journal of Antimicrobial Chemotherapy

JF - Journal of Antimicrobial Chemotherapy

IS - 10

ER -

Kado JH, Salman S, Henderson R, Hand R, Wyber R, Page-Sharp M et al. Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers. Journal of Antimicrobial Chemotherapy. 2020 Oct 1;75(10):2951-2959. Epub 2020 Jul 22. doi: 10.1093/jac/dkaa282

Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers

UN SDGs

Access to Document

Other files and links

The END RHD CRE - Developing an Endgame for Rheumatic Heart Disease in Australia

Optimising usage of the current formulation of benzathine penicillin G for rheumatic fever prevention

Cite this

Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers

UN SDGs

Access to Document

Other files and links

Projects

The END RHD CRE - Developing an Endgame for Rheumatic Heart Disease in Australia

Research output

Optimising usage of the current formulation of benzathine penicillin G for rheumatic fever prevention

Cite this