Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers

Joseph H Kado; Sam Salman; Robert Henderson; Robert Hand; Rosemary Wyber; Madhu Page-Sharp; Kevin Batty; Jonathan Carapetis; Laurens Manning

doi:10.1093/jac/dkaa282

Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers

Joseph H Kado, Sam Salman, Robert Henderson, Robert Hand, Rosemary Wyber, Madhu Page-Sharp, Kevin Batty, Jonathan Carapetis, Laurens Manning

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Original language	English
Pages (from-to)	2951-2959
Number of pages	9
Journal	Journal of Antimicrobial Chemotherapy
Volume	75
Issue number	10
Early online date	22 Jul 2020
DOIs	https://doi.org/10.1093/jac/dkaa282
Publication status	Published - 1 Oct 2020

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10.1093/jac/dkaa282

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Kado, J. H., Salman, S., Henderson, R., Hand, R., Wyber, R., Page-Sharp, M., Batty, K., Carapetis, J., & Manning, L. (2020). Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers. Journal of Antimicrobial Chemotherapy, 75(10), 2951-2959. https://doi.org/10.1093/jac/dkaa282

Kado, Joseph H ; Salman, Sam ; Henderson, Robert et al. / Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection : a randomized, crossover, population pharmacokinetic study in healthy adult volunteers. In: Journal of Antimicrobial Chemotherapy. 2020 ; Vol. 75, No. 10. pp. 2951-2959.

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author = "Kado, {Joseph H} and Sam Salman and Robert Henderson and Robert Hand and Rosemary Wyber and Madhu Page-Sharp and Kevin Batty and Jonathan Carapetis and Laurens Manning",

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Kado, JH, Salman, S, Henderson, R, Hand, R, Wyber, R, Page-Sharp, M, Batty, K, Carapetis, J & Manning, L 2020, 'Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers', Journal of Antimicrobial Chemotherapy, vol. 75, no. 10, pp. 2951-2959. https://doi.org/10.1093/jac/dkaa282

Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers. / Kado, Joseph H; Salman, Sam; Henderson, Robert et al.
In: Journal of Antimicrobial Chemotherapy, Vol. 75, No. 10, 01.10.2020, p. 2951-2959.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

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T2 - a randomized, crossover, population pharmacokinetic study in healthy adult volunteers

AU - Kado, Joseph H

AU - Salman, Sam

AU - Henderson, Robert

AU - Hand, Robert

AU - Wyber, Rosemary

AU - Page-Sharp, Madhu

AU - Batty, Kevin

AU - Carapetis, Jonathan

AU - Manning, Laurens

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Kado JH, Salman S, Henderson R, Hand R, Wyber R, Page-Sharp M et al. Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers. Journal of Antimicrobial Chemotherapy. 2020 Oct 1;75(10):2951-2959. Epub 2020 Jul 22. doi: 10.1093/jac/dkaa282

Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers

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The END RHD CRE - Developing an Endgame for Rheumatic Heart Disease in Australia

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Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers

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The END RHD CRE - Developing an Endgame for Rheumatic Heart Disease in Australia

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