Structured illumination microscopy of living cells

Liisa M. Hirvonen, Trevor A. Smith

Research output: Chapter in Book/Conference paperConference paperpeer-review


One of the recently proposed super-resolution microscopy techniques is structured illumination microscopy (SIM), where a fine grating is projected onto the sample, and the final image is reconstructed from a set of images taken at different grating positions. With this technique, resolution improvement by a factor of two can be achieved compared to conventional wide-field imaging without the need for pulsed lasers, scanning or special properties of the fluorophores. The latest results in the application of this technique to image different subcellular structures at high resolution will be presented.

Original languageEnglish
Title of host publicationConference on Lasers and Electro-Optics/Pacific Rim, CLEOPR 2011
Number of pages3
Publication statusPublished - 1 Dec 2011
Externally publishedYes
EventConference on Lasers and Electro-Optics/Pacific Rim, CLEOPR 2011 - Sydney, Australia
Duration: 28 Aug 20111 Sept 2011

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701


ConferenceConference on Lasers and Electro-Optics/Pacific Rim, CLEOPR 2011


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