Structural requirements for anti-oxidant activity of calix[n]arenes and their associated anti-bacterial activity

Elizabeth Stephens; Y. Tauran; A.W. Coleman; Melinda Fitzgerald

doi:10.1039/c4cc08576k

Structural requirements for anti-oxidant activity of calix[n]arenes and their associated anti-bacterial activity

Elizabeth Stephens, Y. Tauran, A.W. Coleman, Melinda Fitzgerald

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

© 2015 The Royal Society of Chemistry. Treatment of neural cells with calix[n]arenes featuring sulphonate moieties and linked to Ag nanoparticles results in reduced reactive species. For Gram+ bacteria there is an inverse correlation between anti-bacterial activity and ROS reduction whereas for Gram- bacteria only calix[6]arenes bearing O-alkyl sulphonate functions act as ROS inhibitors and anti-bacterial agents.

Original language	English
Pages (from-to)	851-854
Journal	Chemical Communications
Volume	51
Issue number	5
DOIs	https://doi.org/10.1039/c4cc08576k
Publication status	Published - 2015

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title = "Structural requirements for anti-oxidant activity of calix[n]arenes and their associated anti-bacterial activity",

abstract = "{\textcopyright} 2015 The Royal Society of Chemistry. Treatment of neural cells with calix[n]arenes featuring sulphonate moieties and linked to Ag nanoparticles results in reduced reactive species. For Gram+ bacteria there is an inverse correlation between anti-bacterial activity and ROS reduction whereas for Gram- bacteria only calix[6]arenes bearing O-alkyl sulphonate functions act as ROS inhibitors and anti-bacterial agents.",

author = "Elizabeth Stephens and Y. Tauran and A.W. Coleman and Melinda Fitzgerald",

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AU - Stephens, Elizabeth

AU - Tauran, Y.

AU - Coleman, A.W.

AU - Fitzgerald, Melinda

PY - 2015

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AB - © 2015 The Royal Society of Chemistry. Treatment of neural cells with calix[n]arenes featuring sulphonate moieties and linked to Ag nanoparticles results in reduced reactive species. For Gram+ bacteria there is an inverse correlation between anti-bacterial activity and ROS reduction whereas for Gram- bacteria only calix[6]arenes bearing O-alkyl sulphonate functions act as ROS inhibitors and anti-bacterial agents.

U2 - 10.1039/c4cc08576k

DO - 10.1039/c4cc08576k

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JO - Chemical Communications, 2000

JF - Chemical Communications, 2000

SN - 1359-7345

IS - 5

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Structural requirements for anti-oxidant activity of calix[n]arenes and their associated anti-bacterial activity

Abstract

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