Structural requirements for anti-oxidant activity of calix[n]arenes and their associated anti-bacterial activity

Elizabeth Stephens, Y. Tauran, A.W. Coleman, Melinda Fitzgerald

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    13 Citations (Scopus)


    © 2015 The Royal Society of Chemistry. Treatment of neural cells with calix[n]arenes featuring sulphonate moieties and linked to Ag nanoparticles results in reduced reactive species. For Gram+ bacteria there is an inverse correlation between anti-bacterial activity and ROS reduction whereas for Gram- bacteria only calix[6]arenes bearing O-alkyl sulphonate functions act as ROS inhibitors and anti-bacterial agents.
    Original languageEnglish
    Pages (from-to)851-854
    JournalChemical Communications
    Issue number5
    Publication statusPublished - 2015


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