© 2015 The Royal Society of Chemistry. Treatment of neural cells with calix[n]arenes featuring sulphonate moieties and linked to Ag nanoparticles results in reduced reactive species. For Gram+ bacteria there is an inverse correlation between anti-bacterial activity and ROS reduction whereas for Gram- bacteria only calixarenes bearing O-alkyl sulphonate functions act as ROS inhibitors and anti-bacterial agents.
Stephens, E., Tauran, Y., Coleman, A. W., & Fitzgerald, M. (2015). Structural requirements for anti-oxidant activity of calix[n]arenes and their associated anti-bacterial activity. Chemical Communications, 51(5), 851-854. https://doi.org/10.1039/c4cc08576k