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Abstract
There is growing evidence that changes in microvascular structure and function play a role in many
age-related diseases including cardiovascular disease, diabetes, and cancer. Due to the lack of
accessible/available diagnostic modalities tailored to the microvasculature, knowledge of its precise
role in disease pathogenesis and progression is lacking. Optical coherence tomography (OCT) can
provide the resolution and imaging speed required to visualise tissue microstructure and vasculature
in vivo, but has yet to become a clinical standard. This thesis addresses several factors currently
limiting the widespread clinical adoption of OCTA.
age-related diseases including cardiovascular disease, diabetes, and cancer. Due to the lack of
accessible/available diagnostic modalities tailored to the microvasculature, knowledge of its precise
role in disease pathogenesis and progression is lacking. Optical coherence tomography (OCT) can
provide the resolution and imaging speed required to visualise tissue microstructure and vasculature
in vivo, but has yet to become a clinical standard. This thesis addresses several factors currently
limiting the widespread clinical adoption of OCTA.
| Original language | English |
|---|---|
| Qualification | Doctor of Philosophy |
| Awarding Institution |
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| Supervisors/Advisors |
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| Award date | 23 Oct 2023 |
| DOIs | |
| Publication status | Unpublished - 2023 |
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- THESIS - DOCTOR OF PHILOSOPHY - UNTRACHT Gavrielle Rebecca - 2023
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