TY - JOUR
T1 - Stable nickel(0) phosphites as catalysts for C-N cross-coupling reactions
AU - Kampmann, Sven
AU - Sobolev, Alexandre
AU - Koutsantonis, George
AU - Stewart, Scott
PY - 2014
Y1 - 2014
N2 - Herein we describe the design and preparation of inexpensive, air-stable nickel phosphite-based catalysts for use in the C-N cross-coupling reaction. The combination of nickel tetrakis(triphenyl phosphite) {Ni[P(OPh) 3]4} and 1,1'-bis(diphenylphosphino)ferrocene (dppf), and in particular a newly developed catalyst (dppf)Ni[P(OPh)3] 2, were found to be extremely effective in catalyzing a range of amination reactions of anilines and amines with aryl chlorides. This new catalyst system offers an alternative to the bis(cyclooctadienyl)nickel [Ni(COD)2] and palladium(0) catalysts commonly used for C-N bond formation. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
AB - Herein we describe the design and preparation of inexpensive, air-stable nickel phosphite-based catalysts for use in the C-N cross-coupling reaction. The combination of nickel tetrakis(triphenyl phosphite) {Ni[P(OPh) 3]4} and 1,1'-bis(diphenylphosphino)ferrocene (dppf), and in particular a newly developed catalyst (dppf)Ni[P(OPh)3] 2, were found to be extremely effective in catalyzing a range of amination reactions of anilines and amines with aryl chlorides. This new catalyst system offers an alternative to the bis(cyclooctadienyl)nickel [Ni(COD)2] and palladium(0) catalysts commonly used for C-N bond formation. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
U2 - 10.1002/adsc.201400201
DO - 10.1002/adsc.201400201
M3 - Article
SN - 1615-4150
VL - 356
SP - 1967
EP - 1973
JO - ADVANCED SYNTHESIS & CATALYSIS
JF - ADVANCED SYNTHESIS & CATALYSIS
IS - 9
ER -