TY - JOUR
T1 - Spontaneous extrusion of a dexamethasone intravitreal implant (Ozurdex)
AU - Ong, Jessica
AU - Davidoss, Nishant Hemanth
AU - Bhosale, Anant
AU - Balaratnasingam, Chandrakumar
N1 - © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.
PY - 2020/11/3
Y1 - 2020/11/3
N2 - A 59-year-old man with diabetic macular oedema was treated with a dexamethasone intravitreal implant (Ozurdex) to his right eye. Immediately after injection, the implant was noted to have extruded into the perilimbal subconjunctival space. The remnants of the implant were expeditiously removed the following day to avoid corneal decompensation and permanent corneal oedema. Endothelial decompensation secondary to the migration of dexamethasone implants into the subconjunctival space or anterior chamber is a recognised complication of Ozurdex injection. The patient recovered well postoperatively with no further complications. He was planned for a new Ozurdex implant 1 month later.
AB - A 59-year-old man with diabetic macular oedema was treated with a dexamethasone intravitreal implant (Ozurdex) to his right eye. Immediately after injection, the implant was noted to have extruded into the perilimbal subconjunctival space. The remnants of the implant were expeditiously removed the following day to avoid corneal decompensation and permanent corneal oedema. Endothelial decompensation secondary to the migration of dexamethasone implants into the subconjunctival space or anterior chamber is a recognised complication of Ozurdex injection. The patient recovered well postoperatively with no further complications. He was planned for a new Ozurdex implant 1 month later.
KW - Anterior Chamber
KW - Dexamethasone/administration & dosage
KW - Drug Implants/adverse effects
KW - Foreign-Body Migration/diagnosis
KW - Glucocorticoids/administration & dosage
KW - Humans
KW - Intravitreal Injections
KW - Macular Edema/drug therapy
KW - Male
KW - Middle Aged
UR - http://www.scopus.com/inward/record.url?scp=85095675121&partnerID=8YFLogxK
UR - https://casereports.bmj.com/content/13/11/e235102
U2 - 10.1136/bcr-2020-235102
DO - 10.1136/bcr-2020-235102
M3 - Article
C2 - 33148568
SN - 1757-790X
VL - 13
JO - BMJ Case Reports
JF - BMJ Case Reports
IS - 11
M1 - e235102
ER -