Soy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells

Katherine R. Landwehr, Jessica Hillas, Ryan Mead-Hunter, Rebecca A. O'Leary, Anthony Kicic, Benjamin J. Mullins, Alexander N. Larcombe

Research output: Contribution to journalArticle

Abstract

As global biodiesel production increases, there are concerns over the potential health impact of exposure to the exhaust, particularly in regard to young children who are at high risk because of their continuing lung development. Using human airway epithelial cells obtained from young children, we compared the effects of exposure to exhaust generated by a diesel engine with Euro V/VI emission controls running on conventional diesel (ultra-low-sulfur mineral diesel, ULSD), soy biodiesel (B100), or a 20% blend of soy biodiesel with diesel (B20). The exhaust output of biodiesel was found to contain significantly more respiratory irritants, including NOx, CO, and CO2, and a larger overall particle mass. Exposure to biodiesel exhaust resulted in significantly greater cell death and a greater release of immune mediators compared to both air controls and ULSD exhaust. These results have concerning implications for potential global health impacts, particularly for the pediatric population.

Original languageEnglish
JournalEnvironmental Science and Technology
Volume53
Issue number19
DOIs
Publication statusPublished - 1 Oct 2019

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Vehicle Emissions
Biofuels
Poisons
Minerals
diesel
health impact
mineral
Sulfur
sulfur
Health
emission control
diesel engine
Pediatrics
Irritants
Emission control
Cell death
Carbon Monoxide
Diesel engines
Epithelial Cells
air

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Landwehr, Katherine R. ; Hillas, Jessica ; Mead-Hunter, Ryan ; O'Leary, Rebecca A. ; Kicic, Anthony ; Mullins, Benjamin J. ; Larcombe, Alexander N. / Soy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells. In: Environmental Science and Technology. 2019 ; Vol. 53, No. 19.
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abstract = "As global biodiesel production increases, there are concerns over the potential health impact of exposure to the exhaust, particularly in regard to young children who are at high risk because of their continuing lung development. Using human airway epithelial cells obtained from young children, we compared the effects of exposure to exhaust generated by a diesel engine with Euro V/VI emission controls running on conventional diesel (ultra-low-sulfur mineral diesel, ULSD), soy biodiesel (B100), or a 20{\%} blend of soy biodiesel with diesel (B20). The exhaust output of biodiesel was found to contain significantly more respiratory irritants, including NOx, CO, and CO2, and a larger overall particle mass. Exposure to biodiesel exhaust resulted in significantly greater cell death and a greater release of immune mediators compared to both air controls and ULSD exhaust. These results have concerning implications for potential global health impacts, particularly for the pediatric population.",
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Soy biodiesel exhaust is more toxic than mineral diesel exhaust in primary human airway epithelial cells. / Landwehr, Katherine R.; Hillas, Jessica; Mead-Hunter, Ryan; O'Leary, Rebecca A.; Kicic, Anthony; Mullins, Benjamin J.; Larcombe, Alexander N.

In: Environmental Science and Technology, Vol. 53, No. 19, 01.10.2019.

Research output: Contribution to journalArticle

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