Sources and potential transmission of Clostridium difficile in the community of Western Australia

Su Chen Lim

doi:10.26182/5cd22f13b687c

Sources and potential transmission of Clostridium difficile in the community of Western Australia

Su Chen Lim

Research output: Thesis › Doctoral Thesis

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Abstract

The notion that Clostridium difficile infection (CDl) is a hospital-associated disease has been challenged following reports of global increases in community-associated CDl cases and the isolation of clinically-important C. difficile strains from animals. This thesis provides novel and important insights into the prevalence, genotypes, antimicrobial resistance and potential transmission of food and environmental C. difficile in Western Australia (WA ). This work has shown that both food and the general environment in WA are reservoirs for C. difficile that are genetically closely-related to clinical isolates, findings that support the theory of food borne and environmental transmission of CDl.

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	The University of Western Australia
Supervisors/Advisors	Hammer, Kate, Supervisor Foster, Niki, Supervisor Riley, Thomas, Supervisor
Thesis sponsors	Australian Government Research Training Program
Award date	11 Mar 2019
DOIs	https://doi.org/10.26182/5cd22f13b687c
Publication status	Unpublished - 2018

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10.26182/5cd22f13b687c

THESIS - DOCTOR OF PHILOSOPHY - LIM Su Chen - 2018
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Cite this

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title = "Sources and potential transmission of Clostridium difficile in the community of Western Australia",

abstract = "The notion that Clostridium difficile infection (CDl) is a hospital-associated disease has been challenged following reports of global increases in community-associated CDl cases and the isolation of clinically-important C. difficile strains from animals. This thesis provides novel and important insights into the prevalence, genotypes, antimicrobial resistance and potential transmission of food and environmental C. difficile in Western Australia (WA ). This work has shown that both food and the general environment in WA are reservoirs for C. difficile that are genetically closely-related to clinical isolates, findings that support the theory of food borne and environmental transmission of CDl.",

keywords = "Clostridium difficile, epidemiology, foodborne, environmental, Transmission, Clostridium infections, Australia, Zoonosis",

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AB - The notion that Clostridium difficile infection (CDl) is a hospital-associated disease has been challenged following reports of global increases in community-associated CDl cases and the isolation of clinically-important C. difficile strains from animals. This thesis provides novel and important insights into the prevalence, genotypes, antimicrobial resistance and potential transmission of food and environmental C. difficile in Western Australia (WA ). This work has shown that both food and the general environment in WA are reservoirs for C. difficile that are genetically closely-related to clinical isolates, findings that support the theory of food borne and environmental transmission of CDl.

KW - Clostridium difficile

KW - epidemiology

KW - foodborne

KW - environmental

KW - Transmission

KW - Clostridium infections

KW - Australia

KW - Zoonosis

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DO - 10.26182/5cd22f13b687c

M3 - Doctoral Thesis

ER -

Sources and potential transmission of Clostridium difficile in the community of Western Australia

Abstract

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