Somatosensory decision tasks in man: Early and late components of the cerebral potentials evoked by stimulation of different fingers in random sequences

J. E. Desmedt, D. Robertson, E. Brunko, J. Debecker

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

Twenty experiments involving an intramodality somatosensory selective attention tasks were carried out in 12 normal adult motivated subjects. A random sequence of subjectively equivalent electrical stimuli was delivered to 4 fingers in the two hands. The intervals between shocks varied at random between 0.5 and 15 sec (mean 6 sec) in any one finger. The subject was instructed to mentally count the target shocks in a designated finger which was different in alternate runs. The target shocks about 1 mA above subjective threshold elicited large P400 components in the SEP, whereas non-target shocks elicited little, if any, P400. The somewhat more complex findings when strong shocks were delivered according to the same random programme have been discussed. With sequences of weaker shocks, the unitary P400 phenomenon could be studied in single trial SEPs in the best subjects. The early components N20 and P45 of the SEP were not affected by the task conditions, and this was also true for the N140 component. The large P400 to target shocks were of the same voltage at symmetrical parietal locations corresponding to the hand projections.

Original languageEnglish
Pages (from-to)404-415
Number of pages12
JournalElectroencephalography and Clinical Neurophysiology
Volume43
Issue number3
DOIs
Publication statusPublished - 1 Jan 1977
Externally publishedYes

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Evoked Potentials
Fingers
Shock
Hand

Bibliographical note

Electroencephalogr. Clin. Neurophysiol. Cited By :57 Export Date: 1 July 2019 Article CODEN: ECNEA C2 - 70341 Correspondence Address: Desmedt, J.E.; Brain Research Unit, University of Brussels, 115, Boulevard de Waterloo, B 1000 Brussels, Belgium References: Barrett, Halliday, Halliday, Rudolf, The later components of the somatosensory evoked potential and the P300 in a threshold detection task (1977) Cognitive components in event-related cerebral potentials, , J.E. Desmedt, Karger, Basel, (in press); Carmeliet, Debecker, Demaret, A convinient stimulus and situation coding system for the tape recording of event-related potentials (1974) Electroenceph. clin. Neurophysiol., 37, pp. 516-517; Carmeliet, Debecker, Desmedt, A random interval generator using beta ray emission (1971) Electroenceph. clin. Neurophysiol., 30, pp. 354-356; Chapman, Bragdon, Evoked responses to numerical and non-numerical visual stimuli while problem solving (1964) Nature (Lond.), 203, pp. 1155-1157; Courchesne, Hillyard, Galambos, Stimulus novelty, task relevance and the visual evoked potential in man (1975) Electroenceph. clin. Neurophysiol., 39, pp. 131-143; Cracco, The initial positive potential of the human scalp-recorded somatosensory evoked response (1972) Electroenceph. clin. Neurophysiol., 32, pp. 623-629; Debecker, Carmeliet, Automatic suppression of eye movement and muscle artifacts when averaging tape recorded cerebral evoked potentials (1974) Electroenceph. clin. Neurophysiol., 37, pp. 513-515; Debecker, Desmedt, Rate of intermodality switching disclosed by sensory evoked potentials averaged during signal detection tasks (1966) J. Physiol. (Lond.), 185, pp. 52-53; Debecker, Desmedt, Cerebral evoked potential correlates in forced-paced tasks (1971) Nature New Biology, 234, pp. 118-120; Desmedt, Somatosensory cerebral evoked potentials in man (1971) Handbook Electroenceph. clin. Neurophysiol., 9, pp. 8-82. , A. Rémond, Elsevier, Amsterdam; Desmedt, Physiological studies of the efferent recurrent auditory system (1975) Handbook of Sensory Physiology, 5, pp. 219-246. , W.D. Keidel, W.D. Neff, Springer, Berlin, part 2; Desmedt, Some observations on the methodology of cerebral evoked potentials in man (1977) Attention, voluntary contraction and event-related cerebral potentials, pp. 12-29. , J.E. Desmedt, Karger, Basel; Desmedt, Brunko, Somatosensory decision tasks in man: easly and late components of the cerebral potentials evoked by stimulation of different fingers in random sequences. (1977) Electroencephalogr Clin Neurophysiol, , (in press); Desmedt, Debecker, Cerebral event-related potentials in man: dissociation of the cognitive P400 component from slow negative shifts (1977) Brain Res., , (in press); Desmedt, J.E. and Robertson, D. Differential enhancement of early and late components of the cerebral somatosensory evoked potentials during fast sequential cognitive tasks in man. J. Physiol. (Lond.), 271: (in press); Desmedt, Debecker, Manil, Mise en évidence d'un signe électrique cérébral associé à la détection par le sujet, d'un stimulus sensoriel tactile (1965) Bull. Acad. Roy. Med. Belg., 5, pp. 887-936; Desmedt, Brunko, Debecker, Carmeliet, The system bandpass required to avoid distortion of early components when averaging somatosensory evoked potentials (1974) Electroenceph. clin. Neurophysiol., 37, pp. 407-410; Desmedt, Brunko, Debecker, Maturation of the somatosensory evoked potentials in normal infants and children, with particular reference to the early N1 component (1976) Electroenceph. clin. Neurophysiol., 40, pp. 43-58; Donald, Jr., Goff, Attention-related increases in cortical responsivity dissociated from the contingent negative variation (1971) Science, 172, pp. 1163-1166; Donchin, Cohen, Averaged evoked potentials and intramodality selective attention (1967) Electroenceph. clin. Neurophysiol., 22, pp. 537-546; Donchin, Kubovy, Kutas, Johnson, Herning, Graded changes in evoked response (P300) amplitude as a function of cognitive activity (1973) Perception Psychophysics, 14, pp. 319-324; Donchin, Tueting, Ritter, Kutas, Heffley, On the independence of the CNV and the P300 components of the human averaged evoked potential (1975) Electroenceph. clin. Neurophysiol., 38, pp. 449-461; Donchin, Callaway, Cooper, Desmedt, Goff, Hillyard, Sutton, Publication criteria for studies of evoked potentials (EP) in man. Report of a committee (1977) Attention, voluntary contraction and event-related cerebral potentials, pp. 1-11. , J.E. Desmedt, Karger, Basel; Galambos, Hecox, Clinical applications of the brainstem auditory evoked potentials (1977) Auditory evoked cerebral potentials in man. Psychopharmacology correlates of EPs, pp. 1-19. , J.E. Desmedt, Karger, Basel; Giblin, Somatosensory evoked potentials in healthy subjects and in patients with lesions of the nervous system (1964) Ann. N.Y. Acad. Sci., 112, pp. 93-142; Halliday, Changes in the form of cerebral evoked responses in man associated with various lesions of the nervous system. (1967) Electroencephalogr Clin Neurophysiol, pp. 178-192; Halliday, Wakefield, Cerebral evoked potentials in patients with dissociated sensory loss (1963) J. Neurol. Neurosurg. Psychiatr., 26, pp. 211-219; Harter, Salmon, Intra-modality selective attention and evoked cortical potentials to randomly presented patterns (1972) Electroencephalography and Clinical Neurophysiology, 32, pp. 605-613; Hillyard, Hink, Schwent, Picton, Electrical signs of selective attention in the human brain (1973) Science, 182, pp. 177-179; Hillyard, Squires, Bauer, Lindsay, Evoked potential correlates of auditory signal detection (1971) Science, 172, pp. 1357-1360; Jewett, Williston, Auditory evoked far fields averaged from the scalp of humans (1971) Brain, 94, pp. 681-696; Karlin, Cognition, preparation, and sensory-evoked potentials (1970) Psychological Bull., 73, pp. 122-136; McCallum, Knott, Event-related slow potentials of the brain: their relation to behavior (1973) Electroenceph. clin. Neurophysiol., p. 390. , suppl. 33; Matthews, Beauchamp, Small, Cervical somato-sensory evoked responses in man (1974) Nature (Lond.), 252, pp. 230-232; Noël, Desmedt, Somatosensory cerebral evoked potentials after vascular lesions of the brainstem and diencephalon (1975) Brain, 98, pp. 113-128; Paul, Sutton, Evoked potential correlates of response criterion in auditory signal detection (1972) Science, 177, pp. 364-372; Picton, Hillyard, Human auditory evoked potentials. II: Effects of attention (1974) Electroenceph. clin. Neurophysiol., 36, pp. 191-199; Picton, Hillyard, Galambos, Schiff, Human auditory attention: a central or peripheral process (1971) Science, 173, pp. 351-353; Picton, Hillyard, Krausz, Galambos, Human auditory evoked potentials. I. Evaluation of components (1974) Electroenceph. clin. Neurophysiol., 36, pp. 179-190; Ritter, Simson, Vaughan, Jr., Association cortex potentials and reaction time in auditory discrimination (1972) Electroenceph. clin. Neurophysiol., 33, pp. 547-555; Ritter, Vaughan, Costa, Orienting and habituation to auditory stimuli: a study of short term changes in average evoked responses (1968) Electroenceph. clin. Neurophysiol., 25, pp. 550-556; Schwent, Hillyard, Evoked potential correlates of selective attention with multi-channel auditory inputs (1975) Electroenceph. clin. Neurophysiol., 38, pp. 131-138; Schwent, Hillyard, Galambos, Selective attention and the auditory vertex potential. Effects of stimulus delivery rate (1976) Electroenceph. clin. Neurophysiol., 40, pp. 604-614; Skinner, Yingling, Central gating mechanisms that regulate event-related potentials and behavior. A neural model for attention (1977) Attention, voluntary contraction and event-related cerebral potentials, pp. 30-69. , J.E. Desmedt, Karger, Basel; Smith, Donchin, Cohen, Starr, Auditory averaged evoked potentials in man during selective binaural listening (1970) Electroenceph. clin. Neurophysiol., 28, pp. 146-152; Squires, Hillyard, Lindsay, Vertex potentials evoked during auditory signal detection: relation to decision criteria (1973) Perception and Psychophysics, 14, pp. 265-272; Sutton, Braren, Zubin, John, Evoked-potential correlates of stimulus uncertainty (1965) Science, 150, pp. 1187-1188; Tueting, Sutton, Zubin, Quantitative evoked potential correlates of the probability of events (1971) Psychophysiology, 7, pp. 385-394; Vaughan, The relationship of brain activity to scalp recordings of event-related potentials (1969) Averaged evoked potentials Washington, pp. 45-94. , E. Donchin, D.B. Lindsley, U.S. Government printing office, NASA-SP-141; Vaughan, Ritter, The sources of auditory evoked responses recorded from the human scalp (1970) Electroenceph. clin. Neurophysiol., 28, pp. 360-367; Williamson, Goff, Allison, Somatosensory evoked responses in patients with unilateral cerebral lesions (1970) Electroenceph. clin. Neurophysiol., 28, pp. 566-575; Worden, Attention and auditory electrophysiology (1966) Progr. Physiol. Psychol., 1, pp. 45-116

Cite this

@article{91586d54ee3648ce94d60f6294ad5f09,
title = "Somatosensory decision tasks in man: Early and late components of the cerebral potentials evoked by stimulation of different fingers in random sequences",
abstract = "Twenty experiments involving an intramodality somatosensory selective attention tasks were carried out in 12 normal adult motivated subjects. A random sequence of subjectively equivalent electrical stimuli was delivered to 4 fingers in the two hands. The intervals between shocks varied at random between 0.5 and 15 sec (mean 6 sec) in any one finger. The subject was instructed to mentally count the target shocks in a designated finger which was different in alternate runs. The target shocks about 1 mA above subjective threshold elicited large P400 components in the SEP, whereas non-target shocks elicited little, if any, P400. The somewhat more complex findings when strong shocks were delivered according to the same random programme have been discussed. With sequences of weaker shocks, the unitary P400 phenomenon could be studied in single trial SEPs in the best subjects. The early components N20 and P45 of the SEP were not affected by the task conditions, and this was also true for the N140 component. The large P400 to target shocks were of the same voltage at symmetrical parietal locations corresponding to the hand projections.",
keywords = "attention clinical trial controlled study decision evoked somatosensory response finger human normal human randomized controlled trial theoretical study Adult Discrimination (Psychology) Electric Stimulation Evoked Potentials Female Fingers Laterality Male Somatosensory Cortex Touch",
author = "Desmedt, {J. E.} and D. Robertson and E. Brunko and J. Debecker",
note = "Electroencephalogr. Clin. Neurophysiol. Cited By :57 Export Date: 1 July 2019 Article CODEN: ECNEA C2 - 70341 Correspondence Address: Desmedt, J.E.; Brain Research Unit, University of Brussels, 115, Boulevard de Waterloo, B 1000 Brussels, Belgium References: Barrett, Halliday, Halliday, Rudolf, The later components of the somatosensory evoked potential and the P300 in a threshold detection task (1977) Cognitive components in event-related cerebral potentials, , J.E. Desmedt, Karger, Basel, (in press); Carmeliet, Debecker, Demaret, A convinient stimulus and situation coding system for the tape recording of event-related potentials (1974) Electroenceph. clin. Neurophysiol., 37, pp. 516-517; Carmeliet, Debecker, Desmedt, A random interval generator using beta ray emission (1971) Electroenceph. clin. Neurophysiol., 30, pp. 354-356; Chapman, Bragdon, Evoked responses to numerical and non-numerical visual stimuli while problem solving (1964) Nature (Lond.), 203, pp. 1155-1157; Courchesne, Hillyard, Galambos, Stimulus novelty, task relevance and the visual evoked potential in man (1975) Electroenceph. clin. Neurophysiol., 39, pp. 131-143; Cracco, The initial positive potential of the human scalp-recorded somatosensory evoked response (1972) Electroenceph. clin. Neurophysiol., 32, pp. 623-629; Debecker, Carmeliet, Automatic suppression of eye movement and muscle artifacts when averaging tape recorded cerebral evoked potentials (1974) Electroenceph. clin. Neurophysiol., 37, pp. 513-515; Debecker, Desmedt, Rate of intermodality switching disclosed by sensory evoked potentials averaged during signal detection tasks (1966) J. Physiol. (Lond.), 185, pp. 52-53; Debecker, Desmedt, Cerebral evoked potential correlates in forced-paced tasks (1971) Nature New Biology, 234, pp. 118-120; Desmedt, Somatosensory cerebral evoked potentials in man (1971) Handbook Electroenceph. clin. Neurophysiol., 9, pp. 8-82. , A. R{\'e}mond, Elsevier, Amsterdam; Desmedt, Physiological studies of the efferent recurrent auditory system (1975) Handbook of Sensory Physiology, 5, pp. 219-246. , W.D. Keidel, W.D. Neff, Springer, Berlin, part 2; Desmedt, Some observations on the methodology of cerebral evoked potentials in man (1977) Attention, voluntary contraction and event-related cerebral potentials, pp. 12-29. , J.E. Desmedt, Karger, Basel; Desmedt, Brunko, Somatosensory decision tasks in man: easly and late components of the cerebral potentials evoked by stimulation of different fingers in random sequences. (1977) Electroencephalogr Clin Neurophysiol, , (in press); Desmedt, Debecker, Cerebral event-related potentials in man: dissociation of the cognitive P400 component from slow negative shifts (1977) Brain Res., , (in press); Desmedt, J.E. and Robertson, D. Differential enhancement of early and late components of the cerebral somatosensory evoked potentials during fast sequential cognitive tasks in man. J. Physiol. (Lond.), 271: (in press); Desmedt, Debecker, Manil, Mise en {\'e}vidence d'un signe {\'e}lectrique c{\'e}r{\'e}bral associ{\'e} {\`a} la d{\'e}tection par le sujet, d'un stimulus sensoriel tactile (1965) Bull. Acad. Roy. Med. Belg., 5, pp. 887-936; Desmedt, Brunko, Debecker, Carmeliet, The system bandpass required to avoid distortion of early components when averaging somatosensory evoked potentials (1974) Electroenceph. clin. Neurophysiol., 37, pp. 407-410; Desmedt, Brunko, Debecker, Maturation of the somatosensory evoked potentials in normal infants and children, with particular reference to the early N1 component (1976) Electroenceph. clin. Neurophysiol., 40, pp. 43-58; Donald, Jr., Goff, Attention-related increases in cortical responsivity dissociated from the contingent negative variation (1971) Science, 172, pp. 1163-1166; Donchin, Cohen, Averaged evoked potentials and intramodality selective attention (1967) Electroenceph. clin. Neurophysiol., 22, pp. 537-546; Donchin, Kubovy, Kutas, Johnson, Herning, Graded changes in evoked response (P300) amplitude as a function of cognitive activity (1973) Perception Psychophysics, 14, pp. 319-324; Donchin, Tueting, Ritter, Kutas, Heffley, On the independence of the CNV and the P300 components of the human averaged evoked potential (1975) Electroenceph. clin. Neurophysiol., 38, pp. 449-461; Donchin, Callaway, Cooper, Desmedt, Goff, Hillyard, Sutton, Publication criteria for studies of evoked potentials (EP) in man. Report of a committee (1977) Attention, voluntary contraction and event-related cerebral potentials, pp. 1-11. , J.E. Desmedt, Karger, Basel; Galambos, Hecox, Clinical applications of the brainstem auditory evoked potentials (1977) Auditory evoked cerebral potentials in man. Psychopharmacology correlates of EPs, pp. 1-19. , J.E. Desmedt, Karger, Basel; Giblin, Somatosensory evoked potentials in healthy subjects and in patients with lesions of the nervous system (1964) Ann. N.Y. Acad. Sci., 112, pp. 93-142; Halliday, Changes in the form of cerebral evoked responses in man associated with various lesions of the nervous system. (1967) Electroencephalogr Clin Neurophysiol, pp. 178-192; Halliday, Wakefield, Cerebral evoked potentials in patients with dissociated sensory loss (1963) J. Neurol. Neurosurg. Psychiatr., 26, pp. 211-219; Harter, Salmon, Intra-modality selective attention and evoked cortical potentials to randomly presented patterns (1972) Electroencephalography and Clinical Neurophysiology, 32, pp. 605-613; Hillyard, Hink, Schwent, Picton, Electrical signs of selective attention in the human brain (1973) Science, 182, pp. 177-179; Hillyard, Squires, Bauer, Lindsay, Evoked potential correlates of auditory signal detection (1971) Science, 172, pp. 1357-1360; Jewett, Williston, Auditory evoked far fields averaged from the scalp of humans (1971) Brain, 94, pp. 681-696; Karlin, Cognition, preparation, and sensory-evoked potentials (1970) Psychological Bull., 73, pp. 122-136; McCallum, Knott, Event-related slow potentials of the brain: their relation to behavior (1973) Electroenceph. clin. Neurophysiol., p. 390. , suppl. 33; Matthews, Beauchamp, Small, Cervical somato-sensory evoked responses in man (1974) Nature (Lond.), 252, pp. 230-232; No{\"e}l, Desmedt, Somatosensory cerebral evoked potentials after vascular lesions of the brainstem and diencephalon (1975) Brain, 98, pp. 113-128; Paul, Sutton, Evoked potential correlates of response criterion in auditory signal detection (1972) Science, 177, pp. 364-372; Picton, Hillyard, Human auditory evoked potentials. II: Effects of attention (1974) Electroenceph. clin. Neurophysiol., 36, pp. 191-199; Picton, Hillyard, Galambos, Schiff, Human auditory attention: a central or peripheral process (1971) Science, 173, pp. 351-353; Picton, Hillyard, Krausz, Galambos, Human auditory evoked potentials. I. Evaluation of components (1974) Electroenceph. clin. Neurophysiol., 36, pp. 179-190; Ritter, Simson, Vaughan, Jr., Association cortex potentials and reaction time in auditory discrimination (1972) Electroenceph. clin. Neurophysiol., 33, pp. 547-555; Ritter, Vaughan, Costa, Orienting and habituation to auditory stimuli: a study of short term changes in average evoked responses (1968) Electroenceph. clin. Neurophysiol., 25, pp. 550-556; Schwent, Hillyard, Evoked potential correlates of selective attention with multi-channel auditory inputs (1975) Electroenceph. clin. Neurophysiol., 38, pp. 131-138; Schwent, Hillyard, Galambos, Selective attention and the auditory vertex potential. Effects of stimulus delivery rate (1976) Electroenceph. clin. Neurophysiol., 40, pp. 604-614; Skinner, Yingling, Central gating mechanisms that regulate event-related potentials and behavior. A neural model for attention (1977) Attention, voluntary contraction and event-related cerebral potentials, pp. 30-69. , J.E. Desmedt, Karger, Basel; Smith, Donchin, Cohen, Starr, Auditory averaged evoked potentials in man during selective binaural listening (1970) Electroenceph. clin. Neurophysiol., 28, pp. 146-152; Squires, Hillyard, Lindsay, Vertex potentials evoked during auditory signal detection: relation to decision criteria (1973) Perception and Psychophysics, 14, pp. 265-272; Sutton, Braren, Zubin, John, Evoked-potential correlates of stimulus uncertainty (1965) Science, 150, pp. 1187-1188; Tueting, Sutton, Zubin, Quantitative evoked potential correlates of the probability of events (1971) Psychophysiology, 7, pp. 385-394; Vaughan, The relationship of brain activity to scalp recordings of event-related potentials (1969) Averaged evoked potentials Washington, pp. 45-94. , E. Donchin, D.B. Lindsley, U.S. Government printing office, NASA-SP-141; Vaughan, Ritter, The sources of auditory evoked responses recorded from the human scalp (1970) Electroenceph. clin. Neurophysiol., 28, pp. 360-367; Williamson, Goff, Allison, Somatosensory evoked responses in patients with unilateral cerebral lesions (1970) Electroenceph. clin. Neurophysiol., 28, pp. 566-575; Worden, Attention and auditory electrophysiology (1966) Progr. Physiol. Psychol., 1, pp. 45-116",
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TY - JOUR

T1 - Somatosensory decision tasks in man

T2 - Early and late components of the cerebral potentials evoked by stimulation of different fingers in random sequences

AU - Desmedt, J. E.

AU - Robertson, D.

AU - Brunko, E.

AU - Debecker, J.

N1 - Electroencephalogr. Clin. Neurophysiol. Cited By :57 Export Date: 1 July 2019 Article CODEN: ECNEA C2 - 70341 Correspondence Address: Desmedt, J.E.; Brain Research Unit, University of Brussels, 115, Boulevard de Waterloo, B 1000 Brussels, Belgium References: Barrett, Halliday, Halliday, Rudolf, The later components of the somatosensory evoked potential and the P300 in a threshold detection task (1977) Cognitive components in event-related cerebral potentials, , J.E. Desmedt, Karger, Basel, (in press); Carmeliet, Debecker, Demaret, A convinient stimulus and situation coding system for the tape recording of event-related potentials (1974) Electroenceph. clin. Neurophysiol., 37, pp. 516-517; Carmeliet, Debecker, Desmedt, A random interval generator using beta ray emission (1971) Electroenceph. clin. Neurophysiol., 30, pp. 354-356; Chapman, Bragdon, Evoked responses to numerical and non-numerical visual stimuli while problem solving (1964) Nature (Lond.), 203, pp. 1155-1157; Courchesne, Hillyard, Galambos, Stimulus novelty, task relevance and the visual evoked potential in man (1975) Electroenceph. clin. Neurophysiol., 39, pp. 131-143; Cracco, The initial positive potential of the human scalp-recorded somatosensory evoked response (1972) Electroenceph. clin. Neurophysiol., 32, pp. 623-629; Debecker, Carmeliet, Automatic suppression of eye movement and muscle artifacts when averaging tape recorded cerebral evoked potentials (1974) Electroenceph. clin. Neurophysiol., 37, pp. 513-515; Debecker, Desmedt, Rate of intermodality switching disclosed by sensory evoked potentials averaged during signal detection tasks (1966) J. Physiol. (Lond.), 185, pp. 52-53; Debecker, Desmedt, Cerebral evoked potential correlates in forced-paced tasks (1971) Nature New Biology, 234, pp. 118-120; Desmedt, Somatosensory cerebral evoked potentials in man (1971) Handbook Electroenceph. clin. Neurophysiol., 9, pp. 8-82. , A. Rémond, Elsevier, Amsterdam; Desmedt, Physiological studies of the efferent recurrent auditory system (1975) Handbook of Sensory Physiology, 5, pp. 219-246. , W.D. Keidel, W.D. Neff, Springer, Berlin, part 2; Desmedt, Some observations on the methodology of cerebral evoked potentials in man (1977) Attention, voluntary contraction and event-related cerebral potentials, pp. 12-29. , J.E. Desmedt, Karger, Basel; Desmedt, Brunko, Somatosensory decision tasks in man: easly and late components of the cerebral potentials evoked by stimulation of different fingers in random sequences. (1977) Electroencephalogr Clin Neurophysiol, , (in press); Desmedt, Debecker, Cerebral event-related potentials in man: dissociation of the cognitive P400 component from slow negative shifts (1977) Brain Res., , (in press); Desmedt, J.E. and Robertson, D. Differential enhancement of early and late components of the cerebral somatosensory evoked potentials during fast sequential cognitive tasks in man. J. Physiol. (Lond.), 271: (in press); Desmedt, Debecker, Manil, Mise en évidence d'un signe électrique cérébral associé à la détection par le sujet, d'un stimulus sensoriel tactile (1965) Bull. Acad. Roy. Med. Belg., 5, pp. 887-936; Desmedt, Brunko, Debecker, Carmeliet, The system bandpass required to avoid distortion of early components when averaging somatosensory evoked potentials (1974) Electroenceph. clin. Neurophysiol., 37, pp. 407-410; Desmedt, Brunko, Debecker, Maturation of the somatosensory evoked potentials in normal infants and children, with particular reference to the early N1 component (1976) Electroenceph. clin. Neurophysiol., 40, pp. 43-58; Donald, Jr., Goff, Attention-related increases in cortical responsivity dissociated from the contingent negative variation (1971) Science, 172, pp. 1163-1166; Donchin, Cohen, Averaged evoked potentials and intramodality selective attention (1967) Electroenceph. clin. Neurophysiol., 22, pp. 537-546; Donchin, Kubovy, Kutas, Johnson, Herning, Graded changes in evoked response (P300) amplitude as a function of cognitive activity (1973) Perception Psychophysics, 14, pp. 319-324; Donchin, Tueting, Ritter, Kutas, Heffley, On the independence of the CNV and the P300 components of the human averaged evoked potential (1975) Electroenceph. clin. Neurophysiol., 38, pp. 449-461; Donchin, Callaway, Cooper, Desmedt, Goff, Hillyard, Sutton, Publication criteria for studies of evoked potentials (EP) in man. Report of a committee (1977) Attention, voluntary contraction and event-related cerebral potentials, pp. 1-11. , J.E. Desmedt, Karger, Basel; Galambos, Hecox, Clinical applications of the brainstem auditory evoked potentials (1977) Auditory evoked cerebral potentials in man. Psychopharmacology correlates of EPs, pp. 1-19. , J.E. Desmedt, Karger, Basel; Giblin, Somatosensory evoked potentials in healthy subjects and in patients with lesions of the nervous system (1964) Ann. N.Y. Acad. Sci., 112, pp. 93-142; Halliday, Changes in the form of cerebral evoked responses in man associated with various lesions of the nervous system. (1967) Electroencephalogr Clin Neurophysiol, pp. 178-192; Halliday, Wakefield, Cerebral evoked potentials in patients with dissociated sensory loss (1963) J. Neurol. Neurosurg. Psychiatr., 26, pp. 211-219; Harter, Salmon, Intra-modality selective attention and evoked cortical potentials to randomly presented patterns (1972) Electroencephalography and Clinical Neurophysiology, 32, pp. 605-613; Hillyard, Hink, Schwent, Picton, Electrical signs of selective attention in the human brain (1973) Science, 182, pp. 177-179; Hillyard, Squires, Bauer, Lindsay, Evoked potential correlates of auditory signal detection (1971) Science, 172, pp. 1357-1360; Jewett, Williston, Auditory evoked far fields averaged from the scalp of humans (1971) Brain, 94, pp. 681-696; Karlin, Cognition, preparation, and sensory-evoked potentials (1970) Psychological Bull., 73, pp. 122-136; McCallum, Knott, Event-related slow potentials of the brain: their relation to behavior (1973) Electroenceph. clin. Neurophysiol., p. 390. , suppl. 33; Matthews, Beauchamp, Small, Cervical somato-sensory evoked responses in man (1974) Nature (Lond.), 252, pp. 230-232; Noël, Desmedt, Somatosensory cerebral evoked potentials after vascular lesions of the brainstem and diencephalon (1975) Brain, 98, pp. 113-128; Paul, Sutton, Evoked potential correlates of response criterion in auditory signal detection (1972) Science, 177, pp. 364-372; Picton, Hillyard, Human auditory evoked potentials. II: Effects of attention (1974) Electroenceph. clin. Neurophysiol., 36, pp. 191-199; Picton, Hillyard, Galambos, Schiff, Human auditory attention: a central or peripheral process (1971) Science, 173, pp. 351-353; Picton, Hillyard, Krausz, Galambos, Human auditory evoked potentials. I. Evaluation of components (1974) Electroenceph. clin. Neurophysiol., 36, pp. 179-190; Ritter, Simson, Vaughan, Jr., Association cortex potentials and reaction time in auditory discrimination (1972) Electroenceph. clin. Neurophysiol., 33, pp. 547-555; Ritter, Vaughan, Costa, Orienting and habituation to auditory stimuli: a study of short term changes in average evoked responses (1968) Electroenceph. clin. Neurophysiol., 25, pp. 550-556; Schwent, Hillyard, Evoked potential correlates of selective attention with multi-channel auditory inputs (1975) Electroenceph. clin. Neurophysiol., 38, pp. 131-138; Schwent, Hillyard, Galambos, Selective attention and the auditory vertex potential. Effects of stimulus delivery rate (1976) Electroenceph. clin. Neurophysiol., 40, pp. 604-614; Skinner, Yingling, Central gating mechanisms that regulate event-related potentials and behavior. A neural model for attention (1977) Attention, voluntary contraction and event-related cerebral potentials, pp. 30-69. , J.E. Desmedt, Karger, Basel; Smith, Donchin, Cohen, Starr, Auditory averaged evoked potentials in man during selective binaural listening (1970) Electroenceph. clin. Neurophysiol., 28, pp. 146-152; Squires, Hillyard, Lindsay, Vertex potentials evoked during auditory signal detection: relation to decision criteria (1973) Perception and Psychophysics, 14, pp. 265-272; Sutton, Braren, Zubin, John, Evoked-potential correlates of stimulus uncertainty (1965) Science, 150, pp. 1187-1188; Tueting, Sutton, Zubin, Quantitative evoked potential correlates of the probability of events (1971) Psychophysiology, 7, pp. 385-394; Vaughan, The relationship of brain activity to scalp recordings of event-related potentials (1969) Averaged evoked potentials Washington, pp. 45-94. , E. Donchin, D.B. Lindsley, U.S. Government printing office, NASA-SP-141; Vaughan, Ritter, The sources of auditory evoked responses recorded from the human scalp (1970) Electroenceph. clin. Neurophysiol., 28, pp. 360-367; Williamson, Goff, Allison, Somatosensory evoked responses in patients with unilateral cerebral lesions (1970) Electroenceph. clin. Neurophysiol., 28, pp. 566-575; Worden, Attention and auditory electrophysiology (1966) Progr. Physiol. Psychol., 1, pp. 45-116

PY - 1977/1/1

Y1 - 1977/1/1

N2 - Twenty experiments involving an intramodality somatosensory selective attention tasks were carried out in 12 normal adult motivated subjects. A random sequence of subjectively equivalent electrical stimuli was delivered to 4 fingers in the two hands. The intervals between shocks varied at random between 0.5 and 15 sec (mean 6 sec) in any one finger. The subject was instructed to mentally count the target shocks in a designated finger which was different in alternate runs. The target shocks about 1 mA above subjective threshold elicited large P400 components in the SEP, whereas non-target shocks elicited little, if any, P400. The somewhat more complex findings when strong shocks were delivered according to the same random programme have been discussed. With sequences of weaker shocks, the unitary P400 phenomenon could be studied in single trial SEPs in the best subjects. The early components N20 and P45 of the SEP were not affected by the task conditions, and this was also true for the N140 component. The large P400 to target shocks were of the same voltage at symmetrical parietal locations corresponding to the hand projections.

AB - Twenty experiments involving an intramodality somatosensory selective attention tasks were carried out in 12 normal adult motivated subjects. A random sequence of subjectively equivalent electrical stimuli was delivered to 4 fingers in the two hands. The intervals between shocks varied at random between 0.5 and 15 sec (mean 6 sec) in any one finger. The subject was instructed to mentally count the target shocks in a designated finger which was different in alternate runs. The target shocks about 1 mA above subjective threshold elicited large P400 components in the SEP, whereas non-target shocks elicited little, if any, P400. The somewhat more complex findings when strong shocks were delivered according to the same random programme have been discussed. With sequences of weaker shocks, the unitary P400 phenomenon could be studied in single trial SEPs in the best subjects. The early components N20 and P45 of the SEP were not affected by the task conditions, and this was also true for the N140 component. The large P400 to target shocks were of the same voltage at symmetrical parietal locations corresponding to the hand projections.

KW - attention clinical trial controlled study decision evoked somatosensory response finger human normal human randomized controlled trial theoretical study Adult Discrimination (Psychology) Electric Stimulation Evoked Potentials Female Fingers Laterality Mal

UR - http://www.scopus.com/inward/record.url?scp=0017742906&partnerID=8YFLogxK

U2 - 10.1016/0013-4694(77)90263-2

DO - 10.1016/0013-4694(77)90263-2

M3 - Article

VL - 43

SP - 404

EP - 415

JO - Electroencephalography Clinical Neurophysiology

JF - Electroencephalography Clinical Neurophysiology

SN - 0013-4694

IS - 3

ER -