Social reward improves the voluntary control over localized brain activity in fMRI-based neurofeedback training

K.A. Mathiak, E.M. Alawi, Y. Koush, M. Dyck, J.S. Cordes, T.J. Gaber, Florian Zepf, N. Palomero-Gallagher, P. Sarkheil, S. Bergert, M. Zvyagintsev, K. Mathiak

    Research output: Contribution to journalArticlepeer-review

    38 Citations (Scopus)

    Abstract

    © 2015 Mathiak, Alawi, Koush, Dyck, Cordes, Gaber, Zepf, Palomero-Gallagher, Sarkheil, Bergert, Zvyagintsev and Mathiak. Neurofeedback (NF) based on real-time functional magnetic resonance imaging (rt-fMRI) allows voluntary regulation of the activity in a selected brain region. For the training of this regulation, a well-designed feedback system is required. Social reward may serve as an effective incentive in NF paradigms, but its efficiency has not yet been tested. Therefore, we developed a social reward NF paradigm and assessed it in comparison with a typical visual NF paradigm (moving bar). We trained twenty-four healthy participants, on three consecutive days, to control activation in dorsal anterior cingulate cortex (ACC) with fMRI-based NF. In the social feedback group, an avatar gradually smiled when ACC activity increased, whereas in the standard feedback group, a moving bar indicated the activation level. In order to assess a transfer of the NF training both groups were asked to up-regulate their brain activity without receiving feedback immediately before and after the NF training (pre- and post-test). Finally, the effect of the acquired NF training on ACC function was evaluated in a cognitive interference task (Simon task) during the pre- and post-test. Social reward led to stronger activity in the ACC and reward-related areas during the NF training when compared to standard feedback. After the training, both groups were able to regulate ACC without receiving feedback, with a trend for stronger responses in the social feedback group. Moreover, despite a lack of behavioral differences, significant higher ACC activations emerged in the cognitive interference task, reflecting a stronger generalization of the NF training on cognitive interference processing after social feedback. Social reward can increase self-regulation in fMRI-based NF and strengthen its effects on neural processing in related tasks, such as cognitive interference. A particular advantage of social feedback is that a direct external reward is provided as in natural social interactions, opening perspectives for implicit learning paradigms.
    Original languageEnglish
    Pages (from-to)1-14
    JournalFrontiers in Behavioral Neuroscience
    Volume9
    Issue numberJUNE
    DOIs
    Publication statusPublished - 2015

    Fingerprint

    Dive into the research topics of 'Social reward improves the voluntary control over localized brain activity in fMRI-based neurofeedback training'. Together they form a unique fingerprint.

    Cite this