Sleep disruption explains age-related prospective memory deficits: implications for cognitive aging and intervention

Lara Fine, Michael Weinborn, Amanda Ng, Shayne Loft, Yanqi Ryan Li, Erica Hodgson, Denise Parker, Stephanie Rainey Smith, Hamid R. Sohrabi, Belinda Brown, Ralph Martins, Romola S. Bucks

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The high prevalence of sleep disruption among older adults may have implications for cognitive aging, particularly for higher-order aspects of cognition. One domain where sleep disruption may contribute to age-related deficits is prospective memory—the ability to remember to perform deferred actions at the appropriate time in the future. Community-dwelling older adults (55–93 years, N = 133) undertook assessment of sleep using actigraphy and participated in a laboratory-based prospective memory task. After controlling for education, sleep disruption (longer awakenings) was associated with poorer prospective memory. Additionally, longer awakenings mediated the relationship between older age and poorer prospective memory. Other metrics of sleep disruption, including sleep efficiency and wake after sleep onset, were not related to prospective memory, suggesting that examining the features of individual wake episodes rather than total wake time may help clarify relationships between sleep and cognition. The mediating role of awakening length was partially a function of greater depression and poorer executive function (shifting) but not retrospective memory. This study is among the first to examine the association between objectively measured sleep and prospective memory in older adults. Furthermore, this study is novel in suggesting sleep disruption might contribute to age-related prospective memory deficits; perhaps, with implications for cognitive aging more broadly. Our results suggest that there may be opportunities to prevent prospective memory decline by treating sleep problems.

Original languageEnglish
JournalAging, Neuropsychology, and Cognition
DOIs
Publication statusE-pub ahead of print - 30 Aug 2018

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Episodic Memory
Memory Disorders
Sleep
Cognition
Cognitive Aging
Actigraphy
Independent Living
Aptitude
Executive Function
Depression
Efficiency
Education

Cite this

Fine, Lara ; Weinborn, Michael ; Ng, Amanda ; Loft, Shayne ; Li, Yanqi Ryan ; Hodgson, Erica ; Parker, Denise ; Rainey Smith, Stephanie ; Sohrabi, Hamid R. ; Brown, Belinda ; Martins, Ralph ; Bucks, Romola S. / Sleep disruption explains age-related prospective memory deficits : implications for cognitive aging and intervention. In: Aging, Neuropsychology, and Cognition. 2018.
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abstract = "The high prevalence of sleep disruption among older adults may have implications for cognitive aging, particularly for higher-order aspects of cognition. One domain where sleep disruption may contribute to age-related deficits is prospective memory—the ability to remember to perform deferred actions at the appropriate time in the future. Community-dwelling older adults (55–93 years, N = 133) undertook assessment of sleep using actigraphy and participated in a laboratory-based prospective memory task. After controlling for education, sleep disruption (longer awakenings) was associated with poorer prospective memory. Additionally, longer awakenings mediated the relationship between older age and poorer prospective memory. Other metrics of sleep disruption, including sleep efficiency and wake after sleep onset, were not related to prospective memory, suggesting that examining the features of individual wake episodes rather than total wake time may help clarify relationships between sleep and cognition. The mediating role of awakening length was partially a function of greater depression and poorer executive function (shifting) but not retrospective memory. This study is among the first to examine the association between objectively measured sleep and prospective memory in older adults. Furthermore, this study is novel in suggesting sleep disruption might contribute to age-related prospective memory deficits; perhaps, with implications for cognitive aging more broadly. Our results suggest that there may be opportunities to prevent prospective memory decline by treating sleep problems.",
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Sleep disruption explains age-related prospective memory deficits : implications for cognitive aging and intervention. / Fine, Lara; Weinborn, Michael; Ng, Amanda; Loft, Shayne; Li, Yanqi Ryan; Hodgson, Erica; Parker, Denise; Rainey Smith, Stephanie; Sohrabi, Hamid R.; Brown, Belinda; Martins, Ralph; Bucks, Romola S.

In: Aging, Neuropsychology, and Cognition, 30.08.2018.

Research output: Contribution to journalArticle

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AU - Fine, Lara

AU - Weinborn, Michael

AU - Ng, Amanda

AU - Loft, Shayne

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AU - Parker, Denise

AU - Rainey Smith, Stephanie

AU - Sohrabi, Hamid R.

AU - Brown, Belinda

AU - Martins, Ralph

AU - Bucks, Romola S.

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N2 - The high prevalence of sleep disruption among older adults may have implications for cognitive aging, particularly for higher-order aspects of cognition. One domain where sleep disruption may contribute to age-related deficits is prospective memory—the ability to remember to perform deferred actions at the appropriate time in the future. Community-dwelling older adults (55–93 years, N = 133) undertook assessment of sleep using actigraphy and participated in a laboratory-based prospective memory task. After controlling for education, sleep disruption (longer awakenings) was associated with poorer prospective memory. Additionally, longer awakenings mediated the relationship between older age and poorer prospective memory. Other metrics of sleep disruption, including sleep efficiency and wake after sleep onset, were not related to prospective memory, suggesting that examining the features of individual wake episodes rather than total wake time may help clarify relationships between sleep and cognition. The mediating role of awakening length was partially a function of greater depression and poorer executive function (shifting) but not retrospective memory. This study is among the first to examine the association between objectively measured sleep and prospective memory in older adults. Furthermore, this study is novel in suggesting sleep disruption might contribute to age-related prospective memory deficits; perhaps, with implications for cognitive aging more broadly. Our results suggest that there may be opportunities to prevent prospective memory decline by treating sleep problems.

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