Sleep disordered breathing and subclinical impairment of respiratory function are common in sporadic inclusion body myositis

P.M. Rodríguez Cruz, Merrilee Needham, P.N. Hollingsworth, Francis Mastaglia, D.R. Hillman

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

© 2014 Elsevier B.V. Relatively little is known about frequency and extent of respiratory problems in sporadic inclusion body myositis (IBM). To address this issue a study of peripheral muscle and respiratory function and related symptoms was performed in a cohort with biopsy-proven IBM. Dyspnoea, daytime sleepiness, dysphagia, spirometry, respiratory muscle strength, arterial blood gas tensions and ventilation during sleep were assessed. Sixteen patients were studied (10 males; age 68.1±9.9years; disease duration 11.9±5.0years; body mass index 28.5±4.0kg/m2). Four reported excessive daytime sleepiness; 8 had at least mild dysphagia; forced vital capacity was
Original languageEnglish
Pages (from-to)1036-1041
JournalNeuromuscular Disorders
Volume24
Issue number12
DOIs
Publication statusPublished - 2014

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