TY - JOUR
T1 - Single-dose intraoperative radiotherapy during lumpectomy for breast cancer
T2 - an innovative patient-centred treatment
AU - on behalf of the TARGIT-A trial authors
AU - Vaidya, Jayant S.
AU - Bulsara, Max
AU - Baum, Michael
AU - Tobias, Jeffrey S.
AU - Wenz, Frederik
AU - Massarut, Samuele
AU - Pigorsch, Steffi
AU - Alvarado, Michael
AU - Douek, Michael
AU - Saunders, Christobel
AU - Flyger, Henrik L.
AU - Eiermann, Wolfgang
AU - Brew-Graves, Chris
AU - Williams, Norman R.
AU - Potyka, Ingrid
AU - Roberts, Nicholas
AU - Bernstein, Marcelle
AU - Brown, Douglas
AU - Sperk, Elena
AU - Laws, Siobhan
AU - Sütterlin, Marc
AU - Corica, Tammy
AU - Lundgren, Steinar
AU - Holmes, Dennis
AU - Vinante, Lorenzo
AU - Bozza, Fernando
AU - Pazos, Montserrat
AU - Le Blanc-Onfroy, Magali
AU - Gruber, Günther
AU - Polkowski, Wojciech
AU - Dedes, Konstantin J.
AU - Niewald, Marcus
AU - Blohmer, Jens
AU - McCready, David
AU - Hoefer, Richard
AU - Kelemen, Pond
AU - Petralia, Gloria
AU - Falzon, Mary
AU - Joseph, David J.
PY - 2021/4/27
Y1 - 2021/4/27
N2 - In the randomised TARGIT-A trial, risk-adapted targeted intraoperative radiotherapy (TARGIT-IORT) during lumpectomy was non-inferior to whole-breast external beam radiotherapy, for local recurrence. In the long-term, no difference was found in any breast cancer outcome, whereas there were fewer deaths from non-breast-cancer causes. TARGIT-IORT should be included in pre-operative consultations with eligible patients.
AB - In the randomised TARGIT-A trial, risk-adapted targeted intraoperative radiotherapy (TARGIT-IORT) during lumpectomy was non-inferior to whole-breast external beam radiotherapy, for local recurrence. In the long-term, no difference was found in any breast cancer outcome, whereas there were fewer deaths from non-breast-cancer causes. TARGIT-IORT should be included in pre-operative consultations with eligible patients.
UR - https://www.scopus.com/pages/publications/85100475224
U2 - 10.1038/s41416-020-01233-5
DO - 10.1038/s41416-020-01233-5
M3 - Comment/debate
C2 - 33531693
AN - SCOPUS:85100475224
SN - 0007-0920
VL - 124
SP - 1469
EP - 1474
JO - British Journal of Cancer
JF - British Journal of Cancer
IS - 9
ER -
