Simulation of intracranial hemodynamics by an efficient and accurate immersed boundary scheme

Dimitrios S. Lampropoulos, George Bourantas, Benjamin Zwick, George C. Kagadis, Adam Wittek, Karol Miller, Vassilios C. Loukopoulos

Research output: Contribution to journalArticlepeer-review


We use computational fuid dynamics (CFD) to simulate blood flow in intracranial aneurysms (IAs). Despite ongoing improvements in the accuracy and efficiency of body-fitted CFD solvers, generation of a high quality mesh appears as the bottleneck of the flow simulation and strongly affects the accuracy of the numerical solution. To overcome this drawback, we use an Immersed Boundary (IB) method. The proposed approach solves the incompressible Navier-Stokes(N-S) equations on a rectangular (box) domain discretized using uniform Cartesian grid using the finite element method. The immersed object is represented by a set of points (Lagrangian points) located on the surface of the object. Grid local refinement is applied using an automated algorithm. We verify and validate the proposed method by comparing our numerical findings with published experimental results and analytical solutions. We demonstrate the applicability of the proposed scheme on patient-specific blood flow simulations in intracranial aneurysms
Original languageEnglish
Number of pages22
JournalInternational Journal for Numerical Methods in Biomedical Engineering
Publication statusE-pub ahead of print - 26 Aug 2021


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