'SILVAMP TB LAM' rapid urine tuberculosis test predicts mortality in hospitalized HIV patients in South Africa

Bianca Sossen; Tobias Broger; Andrew D Kerkhoff; Charlotte Schutz; Andre Trollip; Emmanuel Moreau; Samuel G Schumacher; Rosie Burton; Amy Ward; Robert J Wilkinson; David A Barr; Mark P Nicol; Claudia M Denkinger; Graeme Meintjes

doi:10.1093/cid/ciaa024

'SILVAMP TB LAM' rapid urine tuberculosis test predicts mortality in hospitalized HIV patients in South Africa

Bianca Sossen, Tobias Broger, Andrew D Kerkhoff, Charlotte Schutz, Andre Trollip, Emmanuel Moreau, Samuel G Schumacher, Rosie Burton, Amy Ward, Robert J Wilkinson, David A Barr, Mark P Nicol, Claudia M Denkinger, Graeme Meintjes

Research output: Contribution to journal › Review article › peer-review

10 Citations (Scopus)

Abstract

Reducing diagnostic delay is key towards decreasing tuberculosis-associated deaths in people living with HIV. In tuberculosis patients with retrospective urine testing, the point-of-care Fujifilm SILVAMP TB LAM (FujiLAM) could have rapidly diagnosed tuberculosis in up to 89% who died. In FujiLAM negative patients, the probability of 12-week survival was 86-97%.

Original language	English
Pages (from-to)	1973-1976
Number of pages	4
Journal	Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Volume	71
Issue number	8
Early online date	9 Jan 2020
DOIs	https://doi.org/10.1093/cid/ciaa024
Publication status	Published - 15 Oct 2020

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10.1093/cid/ciaa024Licence: CC BY

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Sossen, B., Broger, T., Kerkhoff, A. D., Schutz, C., Trollip, A., Moreau, E., Schumacher, S. G., Burton, R., Ward, A., Wilkinson, R. J., Barr, D. A., Nicol, M. P., Denkinger, C. M., & Meintjes, G. (2020). 'SILVAMP TB LAM' rapid urine tuberculosis test predicts mortality in hospitalized HIV patients in South Africa. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71(8), 1973-1976. https://doi.org/10.1093/cid/ciaa024

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title = "'SILVAMP TB LAM' rapid urine tuberculosis test predicts mortality in hospitalized HIV patients in South Africa",

abstract = "Reducing diagnostic delay is key towards decreasing tuberculosis-associated deaths in people living with HIV. In tuberculosis patients with retrospective urine testing, the point-of-care Fujifilm SILVAMP TB LAM (FujiLAM) could have rapidly diagnosed tuberculosis in up to 89% who died. In FujiLAM negative patients, the probability of 12-week survival was 86-97%.",

author = "Bianca Sossen and Tobias Broger and Kerkhoff, {Andrew D} and Charlotte Schutz and Andre Trollip and Emmanuel Moreau and Schumacher, {Samuel G} and Rosie Burton and Amy Ward and Wilkinson, {Robert J} and Barr, {David A} and Nicol, {Mark P} and Denkinger, {Claudia M} and Graeme Meintjes",

year = "2020",

month = oct,

day = "15",

doi = "10.1093/cid/ciaa024",

language = "English",

volume = "71",

pages = "1973--1976",

journal = "Clinical infectious diseases : an official publication of the Infectious Diseases Society of America",

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number = "8",

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Sossen, B, Broger, T, Kerkhoff, AD, Schutz, C, Trollip, A, Moreau, E, Schumacher, SG, Burton, R, Ward, A, Wilkinson, RJ, Barr, DA, Nicol, MP, Denkinger, CM & Meintjes, G 2020, ''SILVAMP TB LAM' rapid urine tuberculosis test predicts mortality in hospitalized HIV patients in South Africa', Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol. 71, no. 8, pp. 1973-1976. https://doi.org/10.1093/cid/ciaa024

'SILVAMP TB LAM' rapid urine tuberculosis test predicts mortality in hospitalized HIV patients in South Africa. / Sossen, Bianca; Broger, Tobias; Kerkhoff, Andrew D et al.
In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Vol. 71, No. 8, 15.10.2020, p. 1973-1976.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - 'SILVAMP TB LAM' rapid urine tuberculosis test predicts mortality in hospitalized HIV patients in South Africa

AU - Sossen, Bianca

AU - Broger, Tobias

AU - Kerkhoff, Andrew D

AU - Schutz, Charlotte

AU - Trollip, Andre

AU - Moreau, Emmanuel

AU - Schumacher, Samuel G

AU - Burton, Rosie

AU - Ward, Amy

AU - Wilkinson, Robert J

AU - Barr, David A

AU - Nicol, Mark P

AU - Denkinger, Claudia M

AU - Meintjes, Graeme

PY - 2020/10/15

Y1 - 2020/10/15

N2 - Reducing diagnostic delay is key towards decreasing tuberculosis-associated deaths in people living with HIV. In tuberculosis patients with retrospective urine testing, the point-of-care Fujifilm SILVAMP TB LAM (FujiLAM) could have rapidly diagnosed tuberculosis in up to 89% who died. In FujiLAM negative patients, the probability of 12-week survival was 86-97%.

AB - Reducing diagnostic delay is key towards decreasing tuberculosis-associated deaths in people living with HIV. In tuberculosis patients with retrospective urine testing, the point-of-care Fujifilm SILVAMP TB LAM (FujiLAM) could have rapidly diagnosed tuberculosis in up to 89% who died. In FujiLAM negative patients, the probability of 12-week survival was 86-97%.

U2 - 10.1093/cid/ciaa024

DO - 10.1093/cid/ciaa024

M3 - Review article

C2 - 31917832

SN - 1058-4838

VL - 71

SP - 1973

EP - 1976

JO - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

IS - 8

ER -

'SILVAMP TB LAM' rapid urine tuberculosis test predicts mortality in hospitalized HIV patients in South Africa

Abstract

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