Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study

Paul Norman; Wendy Davis; M.T. Coughlan; J.M. Forbes; J. Golledge; Timothy Davis

doi:10.1016/j.jvs.2009.05.058

Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study

Paul Norman, Wendy Davis, M.T. Coughlan, J.M. Forbes, J. Golledge, Timothy Davis

Research output: Contribution to journal › Article › peer-review

14 Citations (Web of Science)

Abstract

Objective: Abdominal aortic aneurysms (AAAs) share common risk factors with atherosclerosis, except for diabetes whichappears protective. The reason for this is unknown. Although increased circulating concentrations of advanced glycationendproducts (AGEs) such as carboxymethyllysine (CML) are associated with occlusive vascular disease, it is possible thattheir effects on the aortic wall explain the paradoxically low incidence of AAAs in diabetes.

Original language	English
Pages (from-to)	626-631
Journal	Journal of Vascular Surgery
Volume	50
Issue number	3
DOIs	https://doi.org/10.1016/j.jvs.2009.05.058
Publication status	Published - 2009

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10.1016/j.jvs.2009.05.058

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title = "Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study",

abstract = "Objective: Abdominal aortic aneurysms (AAAs) share common risk factors with atherosclerosis, except for diabetes whichappears protective. The reason for this is unknown. Although increased circulating concentrations of advanced glycationendproducts (AGEs) such as carboxymethyllysine (CML) are associated with occlusive vascular disease, it is possible thattheir effects on the aortic wall explain the paradoxically low incidence of AAAs in diabetes.",

author = "Paul Norman and Wendy Davis and M.T. Coughlan and J.M. Forbes and J. Golledge and Timothy Davis",

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T1 - Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study

AU - Norman, Paul

AU - Davis, Wendy

AU - Coughlan, M.T.

AU - Forbes, J.M.

AU - Golledge, J.

AU - Davis, Timothy

PY - 2009

Y1 - 2009

N2 - Objective: Abdominal aortic aneurysms (AAAs) share common risk factors with atherosclerosis, except for diabetes whichappears protective. The reason for this is unknown. Although increased circulating concentrations of advanced glycationendproducts (AGEs) such as carboxymethyllysine (CML) are associated with occlusive vascular disease, it is possible thattheir effects on the aortic wall explain the paradoxically low incidence of AAAs in diabetes.

AB - Objective: Abdominal aortic aneurysms (AAAs) share common risk factors with atherosclerosis, except for diabetes whichappears protective. The reason for this is unknown. Although increased circulating concentrations of advanced glycationendproducts (AGEs) such as carboxymethyllysine (CML) are associated with occlusive vascular disease, it is possible thattheir effects on the aortic wall explain the paradoxically low incidence of AAAs in diabetes.

U2 - 10.1016/j.jvs.2009.05.058

DO - 10.1016/j.jvs.2009.05.058

M3 - Article

C2 - 19628355

VL - 50

SP - 626

EP - 631

JO - Journal of Vascular Surgery

JF - Journal of Vascular Surgery

SN - 0741-5214

IS - 3

ER -

Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study

Abstract

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