Segregation of efferent projections to different turns of the guinea pig cochlea

Donald Robertson, Caitrin Jane Anderson, Kenneth S. Cole

    Research output: Contribution to journalArticle

    52 Citations (Scopus)

    Abstract

    Localized intracochlear injections of the fluorescent retrograde label diamidino yellow were used to investigate the organization of efferent projections from the brainstem to different turns of the cochlea, in the guinea pig. It was found that the location of small neurones within the lateral superior olive ipsilateral to the injection varied in a systematic manner when injections proceeded from base to apex of the cochlea. In addition, a cruder form of cochleotopic organization was present in that most of the large medial system efferent neurones were labelled only after injection into the 3 most basal turns of the cochlea. The decline of medial system efferent innervation proceeding from base to apex was most striking for the contralateral efferent neurones. The details of base to apex innervation density were different for the different nuclei of origin of the medial system, implying the existence of complex subsystems within the medial neurone population.

    Original languageEnglish
    Pages (from-to)69-76
    Number of pages8
    JournalHearing Research
    Volume25
    Issue number1
    DOIs
    Publication statusPublished - 1 Jan 1987

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    Cochlea
    Guinea Pigs
    Efferent Neurons
    Injections
    Neurons
    Brain Stem
    Population

    Cite this

    Robertson, Donald ; Anderson, Caitrin Jane ; Cole, Kenneth S. / Segregation of efferent projections to different turns of the guinea pig cochlea. In: Hearing Research. 1987 ; Vol. 25, No. 1. pp. 69-76.
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    Segregation of efferent projections to different turns of the guinea pig cochlea. / Robertson, Donald; Anderson, Caitrin Jane; Cole, Kenneth S.

    In: Hearing Research, Vol. 25, No. 1, 01.01.1987, p. 69-76.

    Research output: Contribution to journalArticle

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