Segmental Congenital Vascular Anomaly With Atrophy, Ulceration and Scarring With Complications in Pregnancy

Anne R. Halbert; Amy Leigh Hall; Cathryn Poulton

doi:10.1111/ajd.14441

Segmental Congenital Vascular Anomaly With Atrophy, Ulceration and Scarring With Complications in Pregnancy

Anne R. Halbert
, Amy Leigh Hall
, Cathryn Poulton

Paediatrics

Research output: Contribution to journal › Article › peer-review

Abstract

A 33-year-old woman with a segmental non-involuting congenital vascular anomaly of the left neck developed pain and ulceration in pregnancy and left-sided Horner's syndrome after delivery. Mutational analysis of affected tissue showed a missense mutation in GNA11 (Glu209) and a second mutation in PIK3CA. Sirolimus therapy resulted in healing of the ulceration and resolution of the Horner's syndrome.

Original language	English
Pages (from-to)	e160-e162
Journal	Australasian Journal of Dermatology
Volume	66
Issue number	3
Early online date	28 Feb 2025
DOIs	https://doi.org/10.1111/ajd.14441
Publication status	Published - May 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1111/ajd.14441Licence: CC BY

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title = "Segmental Congenital Vascular Anomaly With Atrophy, Ulceration and Scarring With Complications in Pregnancy",

abstract = "A 33-year-old woman with a segmental non-involuting congenital vascular anomaly of the left neck developed pain and ulceration in pregnancy and left-sided Horner's syndrome after delivery. Mutational analysis of affected tissue showed a missense mutation in GNA11 (Glu209) and a second mutation in PIK3CA. Sirolimus therapy resulted in healing of the ulceration and resolution of the Horner's syndrome.",

keywords = "Horner's syndrome, pregnancy, segmental vascular malformation, sirolimus",

author = "Halbert, \{Anne R.\} and Hall, \{Amy Leigh\} and Cathryn Poulton",

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AU - Poulton, Cathryn

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N2 - A 33-year-old woman with a segmental non-involuting congenital vascular anomaly of the left neck developed pain and ulceration in pregnancy and left-sided Horner's syndrome after delivery. Mutational analysis of affected tissue showed a missense mutation in GNA11 (Glu209) and a second mutation in PIK3CA. Sirolimus therapy resulted in healing of the ulceration and resolution of the Horner's syndrome.

AB - A 33-year-old woman with a segmental non-involuting congenital vascular anomaly of the left neck developed pain and ulceration in pregnancy and left-sided Horner's syndrome after delivery. Mutational analysis of affected tissue showed a missense mutation in GNA11 (Glu209) and a second mutation in PIK3CA. Sirolimus therapy resulted in healing of the ulceration and resolution of the Horner's syndrome.

KW - Horner's syndrome

KW - pregnancy

KW - segmental vascular malformation

KW - sirolimus

UR - https://www.scopus.com/pages/publications/85218738696

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JF - Australasian Journal of Dermatology

IS - 3

ER -

Segmental Congenital Vascular Anomaly With Atrophy, Ulceration and Scarring With Complications in Pregnancy

Abstract

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