Sedation of sheep following the administration of acepromazine with buprenorphine or morphine is similar

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Abstract

The aim of this study was to compare sedation of sheep with acepromazine and buprenorphine or morphine. Twenty merino sheep received acepromazine (0.03 mg/kg) with buprenorphine (0.02 mg/kg, AB, n = 10) or morphine (0.3 mg/kg, AM, n = 10) by intramuscular injection. Sedation was scored (SS) on a scale from 0 (no sedation) to 10 (heavy sedation). Response to restraint was scored (RS) on a scale from 0 (agitated) to 4 (relaxed). Three independent blinded observers and a single blinded observer determined the SS and RS, respectively. The SSs were summed (maximum 30). Data were compared using a t-test. Data is mean ± SD (95% confidence interval). Each group comprised 2 wethers and 8 ewes. There was no difference between the AB and AM groups: weight 44 ± 3.1 kg and 44.7 ± 3 kg (p = 0.58); SS 4.6 ± 3.2 (2.4–6.9) and 6.6 ± 3.5 (4.1–9.1) (p = 0.21); and RS 1.6 ± 1.3 (0.5–2.7) and 2 ± 1.5 (0.7–3.3) (p = 0.6). No adverse effects of the drugs were observed. Sedation with AB or AM at these doses is similar in sheep without observed adverse effects.

Original languageEnglish
Pages (from-to)41-42
Number of pages2
JournalResearch in Veterinary Science
Volume118
DOIs
Publication statusPublished - 1 Jun 2018

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