Intermittent renewable solar photovoltaic (PV) sources cause reliability and power quality issues in the power system. To alleviate these issues, flexible power point tracking (FPPT) algorithms were introduced. The secant-based FPPT algorithm does not require tuning of any parameter, making it a reliable control algorithm whose performance remains unaffected even after PV modules degradation. This paper focuses on the calculation of initial parameters and the implementation of the secant method-based FPPT algorithm considering PV panel degradation. Simulation and experimental comparisons are made between a conventional FPPT algorithm based on adaptive voltage step-based perturb and observe (PO) method and the secant method-based algorithm during normal and degraded panel state of operation.